Results 101 to 110 of about 8,919 (253)
Chemical Affinity as Material Agency for Naturalizing Contextual Meaning
Information, 2012 Chemical affinity involves the integration of two different types of interaction. One is the interaction operating between a pair of reactants while forming a chemical bond, and the other is the prior interaction between those reactants when they ...
Koichiro Matsuno, Stanley N. Salthe
doaj +1 more source
Scratching the structure of moral agency: insights from philosophy applied to neuroscience. [PDF]
Front Neurosci, 2023 Castro-Toledo FJ +2 more
europepmc +1 more source
The Phenomenal Conservative Approach to Religious Epistemology [PDF]
, 2020 In this chapter, we argue for a phenomenal conservative perspective on religious epistemology and attempt to answer some common criticisms of this ...
Gage, Logan Paul, McAllister, Blake
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
How to Supplement Mentalist Evidentialism: What Are the Fundamental Epistemological Principles? [PDF]
Theoria, 2022 Berghofer P.
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Place Goes Wrong in Treating Mind-brain Relationship
Journal of Philosophical Investigations, 2015 U. T. Place claims that philosophical problems concerning the true nature of mind-brain relationship disappears or is settled adhering to materialism, especially type identity theory of mind. He takes above claim as a reasonable scientific hypothesis.
Mahdi Soleimani Khourmouji
doaj
What to believe about your belief that you're in the good case [PDF]
, 2019 Going about our daily lives in an orderly manner requires us, once we are aware of them, to dismiss many metaphysical possibilities. We take it for granted that we are not brains in vats, or living in the Matrix, or in an extended dream.
Worsnip, Alex
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Do Moral Beliefs Motivate Action? [PDF]
Ethical Theory Moral Pract, 2023 Díaz R.
europepmc +1 more source