Results 251 to 260 of about 40,471 (297)
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The plasticitome of cortical interneurons
Nature Reviews Neuroscience, 2022Hebb postulated that, to store information in the brain, assemblies of excitatory neurons coding for a percept are bound together via associative long-term synaptic plasticity. In this view, it is unclear what role, if any, is carried out by inhibitory interneurons. Indeed, some have argued that inhibitory interneurons are not plastic.
Amanda R. McFarlan +6 more
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Disruption of Interneuron Development [PDF]
Epilepsia, 2005 Summary: Disruption of gamma‐aminobutyric acid (GABAergic) interneuron development during the embryonic and early postnatal periods can have profound neurological and behavioral consequences. Hepatocyte growth factor/scatter factor (HGF/SF) has been identified as an important molecular cue that may guide the movement of interneurons from their ...
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Interneuron Diversity series: Interneuron research – challenges and strategies
Trends in Neurosciences, 2003The field of interneuron research has come of age. An influx of new data has shed light on many areas, but has also highlighted major challenges. The articles in this review series will address several of these challenges, including developing a standardized classification scheme, defining how the integrative properties of interneurons shape their ...
David D, Mott, Raymond, Dingledine
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Interneurons in the basolateral amygdala
Neuropharmacology, 2011The amygdala is a temporal lobe structure that is the center of emotion processing in the mammalian brain. Recent interest in the amygdala arises from its role in processing fear and the relationship of fear to human anxiety. The amygdaloid complex is divided into a number of subnuclei that have extensive intra and extra nuclear connections.
Spampanato, Jay +2 more
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Cortical Interneurons and Their Origins
The Neuroscientist, 2005GABAergic interneurons regulate both the development and function of the cerebral cortex. Multiple studies have demonstrated that many cortical interneurons, possibly all of those in nonprimate mammals, originate in the subcortical telencephalon. Most of these derive from the medial ganglionic eminence, but based on varying degrees of evidence, other ...
Carl, Wonders, Stewart A, Anderson
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Interneuron networks in the hippocampus
Current Opinion in Neurobiology, 2011The hippocampus has contributed enormously to our understanding of the operation of elemental brain circuits, not least through the classification of forebrain interneurons. Understanding the operation of interneuron networks however requires not only a wiring diagram that describes the innervation and postsynaptic targets of different GABAergic cells,
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Thalamic Inhibitory Interneurone
Nature, 1966SINCE the investigations of Renshaw1 and Eccles et al.2 on the central inhibitory action of antidromic impulses in motoneuronal axons, indirect evidence has accumulated which suggests that a similar mechanism occurs at higher levels of the neuraxis3. Physiological identification of neural units responsible for such effects has proved to be technically ...
L A, Marco, T S, Brown
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Interneuron Diversity series: Inhibitory interneurons and network oscillations in vitro
Trends in Neurosciences, 2003In vitro models of rhythms of cognitive relevance, such as gamma (30-80 Hz) and theta (5-12 Hz) rhythms in the hippocampus, demonstrate an absolute requirement for phasic inhibitory synaptic transmission. Such rhythms can occur transiently, of approximately 1 s duration, or persistently, lasting for many hours.
Miles A, Whittington, Roger D, Traub
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Synchronization of Neocortical Interneurons
2003As shown by recent experiments, the Fast-Spiking inhibitory interneurons of the neocortex interact also by electrical synapses (gap-junctions). Moreover, their synchronous discharge enhances their inhibitory control of pyramidal neurons. By using a biophysical model of these interneurons the synchronization properties of a network of two synaptically ...
Chillemi S, Barbi M, Di Garbo A
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Specificity of interneuronal connections
Annals of Anatomy - Anatomischer Anzeiger, 1992A fundamental problem of neurobiological research is how specific connections between individual neurons are established and maintained. In this report different levels of neuronal specificity are described. Some neuronal populations display region specificity, but within the target region they establish synapses with a variety of neurons.
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