Results 261 to 270 of about 118,802 (309)

Interneurons unbound

Nature Reviews Neuroscience, 2001
Local-circuit, gamma-aminobutyric acid-releasing inhibitory interneurons of the hippocampus and cortex have traditionally been considered as the regulators of principal neuron activity--the yin to the excitatory yang. Recent evidence indicates that, in addition to that role, their network connectivity and the properties of their intrinsic voltage-gated
C J, McBain, A, Fisahn
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Interneuron Diversity series: Interneuron research – challenges and strategies

Trends in Neurosciences, 2003
The field of interneuron research has come of age. An influx of new data has shed light on many areas, but has also highlighted major challenges. The articles in this review series will address several of these challenges, including developing a standardized classification scheme, defining how the integrative properties of interneurons shape their ...
David D, Mott, Raymond, Dingledine
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The plasticitome of cortical interneurons

Nature Reviews Neuroscience, 2022
Hebb postulated that, to store information in the brain, assemblies of excitatory neurons coding for a percept are bound together via associative long-term synaptic plasticity. In this view, it is unclear what role, if any, is carried out by inhibitory interneurons. Indeed, some have argued that inhibitory interneurons are not plastic.
Amanda R. McFarlan, Christina Y. C. Chou, Airi Watanabe, Nicole Cherepacha, Maria Haddad, Hannah Owens, P. Jesper Sjöström   +6 more
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Interneurons in the basolateral amygdala

Neuropharmacology, 2011
The amygdala is a temporal lobe structure that is the center of emotion processing in the mammalian brain. Recent interest in the amygdala arises from its role in processing fear and the relationship of fear to human anxiety. The amygdaloid complex is divided into a number of subnuclei that have extensive intra and extra nuclear connections.
Spampanato, Jay, Polepalli, Jai, Sah, Pankaj   +2 more
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Thalamic Inhibitory Interneurone

Nature, 1966
SINCE the investigations of Renshaw1 and Eccles et al.2 on the central inhibitory action of antidromic impulses in motoneuronal axons, indirect evidence has accumulated which suggests that a similar mechanism occurs at higher levels of the neuraxis3. Physiological identification of neural units responsible for such effects has proved to be technically ...
L A, Marco, T S, Brown
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Cortical Interneurons and Their Origins

The Neuroscientist, 2005
GABAergic interneurons regulate both the development and function of the cerebral cortex. Multiple studies have demonstrated that many cortical interneurons, possibly all of those in nonprimate mammals, originate in the subcortical telencephalon. Most of these derive from the medial ganglionic eminence, but based on varying degrees of evidence, other ...
Carl, Wonders, Stewart A, Anderson
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Interneuron networks in the hippocampus

Current Opinion in Neurobiology, 2011
The hippocampus has contributed enormously to our understanding of the operation of elemental brain circuits, not least through the classification of forebrain interneurons. Understanding the operation of interneuron networks however requires not only a wiring diagram that describes the innervation and postsynaptic targets of different GABAergic cells,
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The Cholinergic Interneuron of the Striatum

2010
Cholinergic interneurons make up a tiny fraction of cells in the striatum, but yet are critical modulators of neuronal excitability, synaptic transmission, and synaptic plasticity within the striatal circuitry, primarily through activation of muscarinic receptors.
Joshua A. Goldberg, Charles J. Wilson
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Interneuron Diversity series: Inhibitory interneurons and network oscillations in vitro

Trends in Neurosciences, 2003
In vitro models of rhythms of cognitive relevance, such as gamma (30-80 Hz) and theta (5-12 Hz) rhythms in the hippocampus, demonstrate an absolute requirement for phasic inhibitory synaptic transmission. Such rhythms can occur transiently, of approximately 1 s duration, or persistently, lasting for many hours.
Miles A, Whittington, Roger D, Traub
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Synchronization of Neocortical Interneurons

2003
As shown by recent experiments, the Fast-Spiking inhibitory interneurons of the neocortex interact also by electrical synapses (gap-junctions). Moreover, their synchronous discharge enhances their inhibitory control of pyramidal neurons. By using a biophysical model of these interneurons the synchronization properties of a network of two synaptically ...
Chillemi S, Barbi M, Di Garbo A
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