Results 41 to 50 of about 318,868 (184)
Uncontrollable stress can have a profound effect on an organism’s ability to respond effectively to future stressful situations. Behavior subsequent to uncontrollable stress can vary greatly between individuals, falling on a spectrum between healthy ...
Martine M Mirrione +10 more
doaj +1 more source
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen +9 more
wiley +1 more source
Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang +7 more
wiley +1 more source
Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat, Rhinolophus rouxi [PDF]
1. Horseradish peroxidase was applied by iontophoretic injections to physiologically identified regions of the laryngeal motor nucleus, the nucleus ambiguus in the CF/FM batRhinolophus rouxi. 2.
Rübsamen, R., Schweizer, Hermann
core +1 more source
LRRK2 G2019S mutation is the most common genetic cause of Parkinson's disease but its contribution to nigrostriatal neurodegeneration, particularly in response to mitochondrial dysfunction, remains unclear. hLRRK2*G2019S transgenic mice exhibited early microglial activation and motor alterations, but not increased dopaminergic nigrostriatal ...
Roberto García‐Swinburn +8 more
wiley +1 more source
Acetylcholine release from the midbrain interpeduncular nucleus during anesthesia
AN exceptional local rise in metabolism during general anesthesia has been noted previously in the ventral midbrainʼs highly cholinoceptive interpeduncular nucleus (IPN). We report here a functional correlate.
Hentall, Ian +2 more
core +1 more source
Evolution of the nucleus [PDF]
The nucleus represents a major evolutionary transition. As a consequence of separating translation from transcription many new functions arose, which likely contributed to the remarkable success of eukaryotic cells.
Field, Mark C +4 more
core +1 more source
The role of the habenula in drug addiction
Interest in the habenula has greatly increased in recent years. The habenula is a small brain structure located posterior to the thalamus and adjacent to the third ventricle.
Kenia Marisela Velasquez +3 more
doaj +1 more source
Chemical transmission in the rat interpeduncular nucleus in vitro. [PDF]
We have used a rat brain‐slice preparation to study the effects of some cholinomimetic and amino acid agonists and antagonists on the discharge frequency of neurones in the interpeduncular nucleus (i.p.n.), and on the response of these neurones to electrical stimulation of their main excitatory input, the fasciculus retroflexus of Meynert (f.r.m.).
D A, Brown +2 more
openaire +2 more sources
Abstract figure legend The hippocampus contains a diversity of inhibitory neurons, including somatostatin‐expressing (SST+) and neuronal nitric oxide synthase‐expressing (NOS+) projection neurons that target extrahippocampal brain regions, including the hypothalamic supramammillary area (SuM).
Lauren Glassburn +4 more
wiley +1 more source

