Results 101 to 110 of about 38,238 (296)

SVIM: Structural Variant Identification using Mapped Long Reads

, 2019
Motivation: Structural variants are defined as genomic variants larger than 50bp. They have been shown to affect more bases in any given genome than SNPs or small indels. Additionally, they have great impact on human phenotype and diversity and have been
Heller, D., Vingron, M.
core   +1 more source

The Role of Retrotransposons in Gene Family Expansions: Insights from the Mouse \u3ci\u3eAbp\u3c/i\u3e Gene Family [PDF]

, 2013
Background: Retrotransposons have been suggested to provide a substrate for non-allelic homologous recombination (NAHR) and thereby promote gene family expansion. Their precise role, however, is controversial.
Janoušek, Václav, Karn, Robert C., Laukaitis, Christina M.   +2 more
core   +2 more sources

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Comparison of examination performance and test anxiety during bell‐paced and self‐paced gross anatomy laboratory examinations

Anatomical Sciences Education, EarlyView.
Abstract Pacing during anatomy laboratory examinations may influence both student performance and test anxiety. This study compared bell‐paced (BP) and self‐paced (SP) timing structures to assess their impact on students' test performance, test anxiety, and pacing preferences.
Danielle C. Bentley, Angelo Sotto, Peter Lombardi   +2 more
wiley   +1 more source

The association of the interspersed repetitive KpnI sequences with the nuclear matrix.

Journal of Biological Chemistry, 1985
The KpnI sequences constitute the dominant, long, interspersed repetitive DNA families in primate genomes. These families contain related, but nonidentical sequence subsets, some of which border functional gene domains and are transcribed into RNA. To test whether these sequences perform an organizational function in the nucleus, their association with
Chimera, J. A., Musich, Phillip R.
openaire   +2 more sources

Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning

Anatomical Sciences Education, EarlyView.
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde, Madeleine E. Norris, Jennifer R. Kinder, Barbie Klein, Derek Harmon   +4 more
wiley   +1 more source

Epigenetics and Behçet’s Disease: DNA Methylation Specially Highlighted

Iranian Journal of Allergy, Asthma and Immunology, 2019
Behçet's disease (BD) is a multisystem inflammatory disease with unknown etiology. Although evidence about the pathogenesis of BD is growing, the actual cause of this disease is unclear. Both genetic and epigenetic factors are claimed to play significant
Jafar Farhadi, Mohammad Nouri, Ebrahim Sakhinia, Nasser Samadi, Zohreh Babaloo, Shahriar Alipour, Golamreza Jadideslam, Farhad Pouremamali, Alireza Khabbazi   +8 more
doaj   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

Engineering Biochar‐Derived Functional Materials for High‐Performance Supercapacitors: Design Principles, Mechanisms, and Scalable Strategies

Carbon Energy, EarlyView.
ABSTRACT Biochar has emerged as a useful and adaptable source of carbon for supercapacitor electrodes. Its value comes from the way biomass chemistry, thermal conversion, and activation conditions shape the resulting pore network, surface groups, and degree of carbon ordering.
Soumen Mandal, Avinash C. Mendhe, Mayna Roy, Neha S. Barse, Taejoon Park, Han‐Seung Lee, Haigun Lee   +6 more
wiley   +1 more source

Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty

BMC Genomics, 2009
Background Large-scale genome rearrangements brought about by chromosome breaks underlie numerous inherited diseases, initiate or promote many cancers and are also associated with karyotype diversification during species evolution.
Green Eric D, Carone Dawn M, Longo Mark S, O'Neill Michael J, O'Neill Rachel J   +4 more
doaj   +1 more source