Results 11 to 20 of about 16,625 (164)

Recurrent Potential G-Quadruplex Sequences in Archaeal Genomes

Frontiers in Microbiology, 2021
Evolutionary conservation or over-representation of the potential G-quadruplex sequences (PQS) in genomes are usually considered as a sign of the functional relevance of these sequences. However, uneven base distribution (GC-content) along the genome may
Galina V. Chashchina, Galina V. Chashchina, Anna K. Shchyolkina, Simon V. Kolosov, Artemy D. Beniaminov, Dmitry N. Kaluzhny   +5 more
doaj   +1 more source

Association analysis of repetitive elements and R-loop formation across species

Mobile DNA, 2021
Background Although recent studies have revealed the genome-wide distribution of R-loops, our understanding of R-loop formation is still limited. Genomes are known to have a large number of repetitive elements.
Chao Zeng, Masahiro Onoguchi, Michiaki Hamada   +2 more
doaj   +1 more source

Evaluation of Mammalian Interspersed Repeats to investigate the goat genome

Italian Journal of Animal Science, 2010
Among the repeated sequences present in most eukaryotic genomes, SINEs (Short Interspersed Nuclear Elements) are widely used to investigate evolution in the mammalian order (Buchanan et al., 1999).
P. Mariani, F. Panzitta, A. Stella, C. Gorni   +3 more
doaj   +1 more source

Bovine DNA contains a single major family of interspersed repetitive sequences [PDF]

European Journal of Biochemistry, 1986
A major family of short, interspersed, repeated sequences in the bovine genome has been characterized. This family makes up the majority of all non-satellite repetitive DNA or about 6% of the bovine genome. It is estimated that there are at least 600 000 copies of this family interspersed among non-repetitive DNA sequences. Sequence analysis shows that
K K, Richardson, R M, Crosby, P J, Good, N L, Rosen, J E, Mayfield   +4 more
openaire   +2 more sources

Replicative Senescence-Associated LINE1 Methylation and LINE1-Alu Expression Levels in Human Endothelial Cells

Cells, 2022
One of the main challenges of current research on aging is to identify the complex epigenetic mechanisms involved in the acquisition of the cellular senescent phenotype.
Deborah Ramini, Silvia Latini, Angelica Giuliani, Giulia Matacchione, Jacopo Sabbatinelli, Emanuela Mensà, Maria Giulia Bacalini, Paolo Garagnani, Maria Rita Rippo, Giuseppe Bronte, Massimiliano Bonafè, Maurizio Cardelli, Fabiola Olivieri   +12 more
doaj   +1 more source

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Considering transposable element diversification in de novo annotation approaches. [PDF]

PLoS ONE, 2011
Transposable elements (TEs) are mobile, repetitive DNA sequences that are almost ubiquitous in prokaryotic and eukaryotic genomes. They have a large impact on genome structure, function and evolution.
Timothée Flutre, Elodie Duprat, Catherine Feuillet, Hadi Quesneville   +3 more
doaj   +1 more source

Independent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum. [PDF]

PLoS ONE, 2012
Allopolyploidy (interspecific hybridisation and polyploidy) has played a significant role in the evolutionary history of angiosperms and can result in genomic, epigenetic and transcriptomic perturbations.
Simon Renny-Byfield, Ales Kovařík, Michael Chester, Richard A Nichols, Jiri Macas, Petr Novák, Andrew R Leitch   +6 more
doaj   +1 more source

Similar interstitial deletions of the KAL-1 gene in two Brazilian families with X-linked Kallmann Syndrome

Genetics and Molecular Biology, 2004
Mutations in the KAL-1 gene localized at Xp22.3 have been shown to be responsible for the X-linked Kallmann syndrome (KS), a disorder characterized by the association of hypogonadotropic hypogonadism and anosmia.
Ericka Barbosa Trarbach, Isabella Lopes Monlleo, Carlos Guilherme Gaelzer Porciuncula, Marshall Italo Barros Fontes, Maria Teresa Mathias Baptista, Christine Hackel   +5 more
doaj   +1 more source

Associations between Mycobacterium tuberculosis Strains and Phenotypes

Emerging Infectious Diseases, 2010
To inform development of tuberculosis (TB) control strategies, we characterized a total of 2,261 Mycobacterium tuberculosis complex isolates by using multiple phenotypic and molecular markers, including polymorphisms in repetitive sequences ...
Timothy Brown, Vladyslav Nikolayevskyy, Preya Velji, Francis Drobniewski   +3 more
doaj   +1 more source