Results 11 to 20 of about 38,238 (296)

The distribution of interspersed repetitive DNA sequences in the human genome

Genomics, 1989
The distribution of interspersed repetitive DNA sequences in the human genome has been investigated, using a combination of biochemical, cytological, computational, and recombinant DNA approaches. "Low-resolution" biochemical experiments indicate that the general distribution of repetitive sequences in human DNA can be adequately described by models ...
R K, Moyzis, D C, Torney, J, Meyne, J M, Buckingham, J R, Wu, C, Burks, K M, Sirotkin, W B, Goad   +7 more
openaire   +4 more sources

Interspersion of repetitive with repetitive sequences in an amphibian, Rana berlandieri [PDF]

Nucleic Acids Research, 1980
When conventional genome arrangement analyses performed on R. berlandieri DNA at a normal (60 degrees C) and a high (75 degrees C) reassociation temperature were compared, an additional interspersion pattern was detected which indicates that different classes of repetitive sequences are closely interspersed with each other.
D E, Graham, K E, Schanke
openaire   +2 more sources

Association analysis of repetitive elements and R-loop formation across species

Mobile DNA, 2021
Background Although recent studies have revealed the genome-wide distribution of R-loops, our understanding of R-loop formation is still limited. Genomes are known to have a large number of repetitive elements.
Chao Zeng, Masahiro Onoguchi, Michiaki Hamada   +2 more
doaj   +1 more source

Recurrent Potential G-Quadruplex Sequences in Archaeal Genomes

Frontiers in Microbiology, 2021
Evolutionary conservation or over-representation of the potential G-quadruplex sequences (PQS) in genomes are usually considered as a sign of the functional relevance of these sequences. However, uneven base distribution (GC-content) along the genome may
Galina V. Chashchina, Galina V. Chashchina, Anna K. Shchyolkina, Simon V. Kolosov, Artemy D. Beniaminov, Dmitry N. Kaluzhny   +5 more
doaj   +1 more source

Evaluation of Mammalian Interspersed Repeats to investigate the goat genome

Italian Journal of Animal Science, 2010
Among the repeated sequences present in most eukaryotic genomes, SINEs (Short Interspersed Nuclear Elements) are widely used to investigate evolution in the mammalian order (Buchanan et al., 1999).
P. Mariani, F. Panzitta, A. Stella, C. Gorni   +3 more
doaj   +1 more source

A long, nontranslatable poly(A) RNA stored in the egg of the sea urchin Strongylocentrotus purpuratus [PDF]

, 1988
Nontranslatable transcripts containing interspersed repetitive sequence elements constitute a major fraction of the poly(A) RNA stored in the cytoplasm of both the sea urchin egg and the amphibian oocyte.
Britten, Roy J., Calzone, Frank J., Davidson, Eric H., Le, Nga, Lee, James J.   +4 more
core   +1 more source

Bovine DNA contains a single major family of interspersed repetitive sequences [PDF]

European Journal of Biochemistry, 1986
A major family of short, interspersed, repeated sequences in the bovine genome has been characterized. This family makes up the majority of all non-satellite repetitive DNA or about 6% of the bovine genome. It is estimated that there are at least 600 000 copies of this family interspersed among non-repetitive DNA sequences. Sequence analysis shows that
K K, Richardson, R M, Crosby, P J, Good, N L, Rosen, J E, Mayfield   +4 more
openaire   +2 more sources

Painting of human chromosomes with probes generated from hybrid cell lines by PCR with Alu and L1 primers [PDF]

, 1990
Specific amplification of human sequences of up to several kb length has recently been accomplished in man-hamster and man-mouse somatic hybrid cell DNA by IRS-PCR (interspersed repetitive sequence — polymerase chain reaction).
Cremer, Thomas, Lengauer, Christoph, Riethman, Harold C.   +2 more
core   +1 more source

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Roy J. Britten, 1919–2012: Our early years at Caltech [PDF]

, 2012
Roy Britten died in Costa Mesa, California on January 21, 2012, of pancreatic cancer at age 92. His work in the 1960s, in which he used renaturation kinetics to provide a quantitative image of the single-copy and repetitive sequence content of animal ...
Davidson, Eric H.
core   +1 more source