Results 51 to 60 of about 16,625 (164)

Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty

BMC Genomics, 2009
Background Large-scale genome rearrangements brought about by chromosome breaks underlie numerous inherited diseases, initiate or promote many cancers and are also associated with karyotype diversification during species evolution.
Green Eric D, Carone Dawn M, Longo Mark S, O'Neill Michael J, O'Neill Rachel J   +4 more
doaj   +1 more source

Short, interspersed repetitive DNA sequences in prokaryotic genomes [PDF]

Journal of Bacteriology, 1992
J R, Lupski, G M, Weinstock
openaire   +2 more sources

LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker

npj Precision Oncology
Long interspersed element 1 (LINE-1) retrotransposons are repetitive sequences that can move within the genome by an autonomous mechanism. To limit their mutagenic potential, benign cells restrict LINE-1 expression through molecular mechanisms such as ...
Pamela R. de Santiago, Sho Sato, Stephanie J. Zhang, Meaghan C. Dougher, Kyle M. Devins, Agnes J. Bilecz, Sagar Rayamajhi, Gabriel Mingo, Hannah S. Rendulich, Yi Feng, Connie Wu, Martin S. Taylor, Yelena Zhuravlev, Euihye Jung, Dalia K. Omran, Tian-Li Wang, Ie-Ming Shih, Lauren E. Schwartz, Sarah Kim, Mark A. Morgan, Janos L. Tanyi, Kathleen H. Burns, Ernst Lengyel, Carlos Parra-Herran, Andrew K. Godwin, David R. Walt, Ronny Drapkin   +26 more
doaj   +1 more source

A chromosome-level genome assembly of Cape hare (Lepus capensis)

Scientific Data
The Cape hare (Lepus capensis) is among the most widely distributed hare species globally, inhabiting extensive regions across Africa, the Middle East, and Central Asia. However, evolutionary and genetic research on L.
Xianggui Dong, Yu Liu, Yuan Chen, Xinxin Ping, Zhanjun Ren, Yuanyuan Zhang   +5 more
doaj   +1 more source

Transposable Elements and Their Epigenetic Regulation in Mental Disorders: Current Evidence in the Field

Frontiers in Genetics, 2019
Transposable elements (TEs) are highly repetitive DNA sequences in the human genome that are the relics of previous retrotransposition events. Although the majority of TEs are transcriptionally inactive due to acquired mutations or epigenetic processes ...
Błażej Misiak, Laura Ricceri, Maria M. Sąsiadek   +2 more
doaj   +1 more source

An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers.

PLoS ONE
The autonomous and active Long-Interspersed Element-1 (LINE-1, L1) and the non-autonomous Alu retrotransposon elements, contributing to 30% of the human genome, are the most abundant repeated sequences.
Trang Thi Quynh Tran, Tung The Pham, Than Thi Nguyen, Trang Hien Do, Phuong Thi Thu Luu, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Son Van Ho, Hang Viet Dao, Tong Van Hoang, Lan Thi Thuong Vo   +11 more
doaj   +1 more source

Selective identification of epigenetic regulators at methylated genomic sites by SelectID

Nature Communications
DNA methylation is a significant component in proximal chromatin regulation and plays crucial roles in regulating gene expression and maintaining the repressive state of retrotransposon elements.
Wenchang Qian, Penglei Jiang, Mingming Niu, Yujuan Fu, Deyu Huang, Dong Zhang, Ying Liang, Qiwei Wang, Yingli Han, Xin Zeng, Yixin Shi, Lingli Jiang, Zebin Yu, Jinxin Li, Huan Lu, Hong Wang, Baohui Chen, Pengxu Qian   +17 more
doaj   +1 more source

Comparative Genomic In Situ Hybridization and the Possible Role of Retroelements in the Karyotypic Evolution of Three Akodontini Species

International Journal of Genomics, 2017
South American Akodontini rodents are characterized by a large number of chromosome rearrangements. Among them, the genus Akodon has been extensively analyzed with classical and molecular cytogenetics, which allowed the identification of a large number ...
Naiara Pereira Araújo, Gustavo Campos Silva Kuhn, Flávia Nunes Vieira, Thaís Queiroz Morcatty, Adriano Pereira Paglia, Marta Svartman   +5 more
doaj   +1 more source

Editorial: Mobile elements and plant genome evolution, comparative analyses and computational tools, volume II

Frontiers in Plant Science, 2023
Ruslan Kalendar, Ruslan Kalendar, Gennady I. Karlov   +2 more
doaj   +1 more source

Evolutionary divergent clusters of transcribed extinct truncated retroposons drive low mRNA expression and developmental regulation in the protozoan Leishmania

BMC Biology
Background The Leishmania genome harbors formerly active short interspersed degenerated retroposons (SIDERs) representing the largest family of repetitive elements among trypanosomatids.
Gabriel Reis Ferreira, Jean-Guillaume Emond-Rheault, Lysangela Alves, Philippe Leprohon, Martin A. Smith, Barbara Papadopoulou   +5 more
doaj   +1 more source