Results 1 to 10 of about 77,646 (205)

Neuroregulatory Biomaterials for Intervertebral Disc Regeneration via Neuro-Disc Microenvironment Modulation [PDF]

Research
Intervertebral discs have long been considered to lack neural innervation. However, recent studies have revealed that intervertebral disc degeneration is accompanied by marked pathological nerve invasion.
Ang Li, Xiaohu Li, Yi Yu, Liang Chen, Juan Wang, Wenguo Cui, Xiaodong Liu   +6 more
doaj   +2 more sources

First Report of Intervertebral Disc Calcification in a Black Child in Sub‐Saharan Africa [PDF]

Clinical Case Reports
We report an intervertebral disc calcification in a Black African child who had consulted us for neck pain. The diagnosis of C2–C3 intervertebral disc calcification was made on a standard X‐ray and CT scan.
Yamyelle Enselme Zongo, Ismael Ayouba Tinni, Hamiidah Hunsu‐Horhon Guingani, Yannick Laurent Tchenadoyo Bayala, Aboubakar Ouedraogo, Fulgence Kabore, Wendlassida Stéphanie Joelle Zabsonré/Tiendrebeogo, Dieu‐Donné Ouedraogo   +7 more
doaj   +2 more sources

The role of ageing and oxidative stress in intervertebral disc degeneration

Frontiers in Molecular Biosciences, 2022
Intervertebral disc degeneration (IDD) is the primary cause of intervertebral disc (IVD) disease. With the increased ageing of society, an increasing number of patients are plagued by intervertebral disc disease. Ageing not only accelerates the decreased
Pengfei Wen, Bolong Zheng, Binfei Zhang, Tao Ma, Linjie Hao, Yumin Zhang   +5 more
doaj   +1 more source

Application study of 3D LAVA-Flex on lumbar intervertebral disc degeneration

European Journal of Medical Research, 2021
Background Degeneration of the intervertebral discs are very common diseases, indicating the specific or malignant changes in intervertebral disc component, structure and function.
Tiefang Liu, Yonghao Wang, Zhengyang Xu, Tao Wu, Xiao Zang, Meng Li, Jinfeng Li   +6 more
doaj   +1 more source

Sal003 alleviated intervertebral disc degeneration by inhibiting apoptosis and extracellular matrix degradation through suppressing endoplasmic reticulum stress pathway in rats

Frontiers in Pharmacology, 2023
Apoptosis and extracellular matrix degradation of the nucleus pulposus are the main initiators of intervertebral disc degeneration (IVDD) and can be explained by endoplasmic reticulum (ER) stress.
Yan Chen, Yan Chen, Baixing Li, Baixing Li, Yue Xu, Tangjun Zhou, Tangjun Zhou, Changqing Zhao, Changqing Zhao, Jie Zhao, Jie Zhao   +10 more
doaj   +1 more source

Inhibition of lysyl oxidase accelerates intervertebral disc degeneration induced by apoptosis of nucleus pulposus cells

陆军军医大学学报, 2023
Objective To explore the role and possible mechanism of lysyl oxidase (LOX) in age-related degeneration of intervertebral disc. Methods Six SD rats, aged of 2, 8 and 20 months respectively, were subjected, and then underwent intervertebral disc MRI and X-
LI Jianmin, XING Hui, CHONG Fanli, ZHAO Runzhi   +3 more
doaj   +1 more source

HISTOLOGICAL AND STRUCTURAL STUDY OF PROLAPSED INTERVERTEBRAL DISC [PDF]

Basrah Journal of Surgery, 2006
The research of the etiology of low back pain and right leg pain has been focused on the study of histological degenerative changes of human intervertebral disc prolapse.
Khalida K Jbara, Thamer A Hamdan
doaj   +1 more source

Prolapsed intervertebral disc [PDF]

BMJ, 2008
Prolapsed intervertebral disc is common—it is seen in up to a quarter of magnetic resonance scans and can be detected even in asymptomatic adults.1 Disc prolapse is genetically driven—twin studies indicate that at least 60% of the variance can be explained on genetic grounds and not by the commonly assumed environmental factors (work, trauma, exposure ...
openaire   +2 more sources

Pressure distributions inside intervertebral discs under unilateral pedicle screw fixation in a porcine spine model

Journal of Orthopaedic Surgery and Research, 2018
Background Little data are available regarding the effects of pedicle screws on the intervertebral disc stress for different spinal segments. The aim of this study was to analyze the intervertebral disc stress in response to the placement of pedicle ...
Zhao Meng, Chen Wang, Li-Jun Tian, Xue-Jun Zhang, Dong Guo, Yan Zou   +5 more
doaj   +1 more source

Effect of sIL-13Rα2-Fc on the progression of rat tail intervertebral disc degeneration

Journal of Orthopaedic Surgery and Research, 2019
Background The incidence of degenerative disc disease caused by intervertebral disc injury is increasing annually, seriously affecting the quality of life of patients and increasing the disease burden on society.
Xin Wang, Junhao Sun, Jianshi Tan, Pengzhong Fang, Jinlei Chen, Wen Yuan, Huajiang Chen, Yang Liu   +7 more
doaj   +1 more source