Results 101 to 110 of about 93,770 (350)

Influence of facet joint tropism on the formation of intervertebral disc herniation in the lumbosacral spine

Хирургия позвоночника, 2018
Objective. To evaluate the influence of facet joint tropism on the formation of intervertebral disc hernias in the lumbosacral spine, and to determine the relationship between facet joint asymmetry and the type of hernia of the lumbar intervertebral ...
Vadim A. Byvaltsev, Ivan A. Stepanov, Alena K. Okoneshnikova   +2 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Fascia, Eh. What Is It? What Is It Good for?

Clinical Anatomy, EarlyView.
ABSTRACT Opinions on the meaning of the term fascia appear to have been diverging for the past quarter century. In 1998, the definition of fascia in the international standard anatomical nomenclature was narrowed by removing the term fascia superficialis.
Paul E. Neumann, Heba Labib, Martin Lhuaire, Noel T. Boaz, Geoffroy P. J. C. Noel, Carlos Suárez‐Quian, Chernet Tessema, Peter J. Ward, Anthony J. Weinhaus, Mahindra K. Anand, Alan J. Detton   +10 more
wiley   +1 more source

Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment

Journal of Orthopaedic Translation
As a permanent state of cell cycle arrest, cellular senescence has become an important factor in aging and age-related diseases. As a central regulator of physiology and pathology associated with cellular senescence, the senescence associated secretory ...
Yang Liu, Yiming Dou, Xun Sun, Qiang Yang   +3 more
doaj   +1 more source

Systemic clearance of p16^INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration [PDF]

, 2019
Prashanti Patil, Qing Dong, Dong Wang, Jianhui Chang, Christopher D. Wiley, Marco Demaria, Joon Lee, James D. Kang, Laura J. Niedernhofer, Paul D. Robbins, Gwendolyn Sowa, Judith Campisi, Daohong Zhou, Nam Vo   +13 more
openalex   +1 more source

Construction and Validation of a Preoperative Surgical Difficulty Prediction and Risk Stratification System for Posterior Spinal Deformity Correction Surgery Based on Machine Learning ‐ Multicenter Cohort Study

iMetaMed, EarlyView.
A web calculator, trained on multicenter data with seven Boruta‐selected preoperative features, predicts prolonged operative time for posterior spinal deformity correction to enable individualized planning and optimized operating‐room resources. ABSTRACT Operative duration reflects surgical complexity and is valuable for perioperative planning.
Chan Xu, Jialiang Zheng, Chengliang Yin, Runmin Li, Xubin Quan, Binghao Chen, Zhaohui Hu, Tongqing Luo, Hao Jiang, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Anfa Chen, Xin Zhou, Wei Huang, Sen Gao, Jiali Yu, Zhi‐Ri Tang, Yusi Zhang, Kai Wang, Shi‐Nan Wu, Wencai Liu, Xiangdong Xi, Haizhen Ding, Qiang Liu, Haopeng Luan, Wenle Li   +27 more
wiley   +1 more source

BIOCHEMICAL AND BIOMECHANICAL SUBSTANTIATION OF REPARATIVE REGENERATION OF INTERVERTEBRAL DISCS IN PATIENTS WITH DEGENERATIVE DISC DISEASES

Східноукраїнський медичний журнал, 2020
Degenerative disc diseases occupy the second place in the overall structure of morbidity with temporary disability. In 40% of patients with spinal osteochondrosis, diseases of the locomotor apparatus and connective tissue cause primary disability.
J. A. Bodnarchuk, M. V. Khyzhnjak, О. О. Potapov, N. G. Chopik   +3 more
doaj  

Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells. [PDF]

JOR Spine
Goat nucleus pulposus cells cultured under clinically relevant oxygen, glucose, pH, and osmolarity revealed pH to have the most influential impact on viability and glycosaminoglycan synthesis. Interactions between factors showed that disc cell behavior is shaped by the microenvironment, highlighting its importance in regenerative therapy design for the
Wilson N, Néill TN, McDonnell J, McDonnell E, Brama PAJ, Buckley CT.   +5 more
europepmc   +2 more sources

Leptin and the intervertebral disc: a biochemical link exists between obesity, intervertebral disc degeneration and low back pain—an in vitro study in a bovine model [PDF]

, 2018
Anand Segar, Jeremy Fairbank, Jill Urban
openalex   +1 more source

Analysis of balance in adults with chronic axial spinal pain receiving medial branch block or radiofrequency ablation procedures

PM&R, EarlyView.
Abstract Background Medial branch blocks (MBB) and radiofrequency ablations (RFA) are common diagnostic, prognostic, and interventional procedures performed for the management of cervical and lumbar spine facetogenic pain. Although these procedures have established utility as pain management strategies, it is unclear if the disruption in function of ...
Matthew Carter, John D Ralston, Robert Burnham, Jennifer Laxshimalla, Lisa Jasper, JuliAnn Thai, Ashley D Smith   +6 more
wiley   +1 more source