Results 101 to 110 of about 90,995 (334)

The causality between smoking and intervertebral disc degeneration mediated by IL-1β secreted by macrophage: A Mendelian randomization study

open access: yesHeliyon
There is still a lack of high-level evidence regarding the causal relationship between smoking and intervertebral disc degenerative diseases. This study utilized data from genome wide analysis studies and conducted two-sample Mendelian randomization ...
Zhaopu Han, Yicheng Chen, Xiaojian Ye
doaj   +1 more source

Friction in metal-on-metal total disc arthroplasty: effect of ball radius [PDF]

open access: yes, 2012
Total Disc Arthroplasty (TDA) can be used to replace a degenerated intervertebral disc in the spine. There are different designs of prosthetic discs, but one of the most common is a ball-and-socket combination.
Hukins, DWL   +3 more
core   +1 more source

Novel Antioxidant and Antibacterial Injectable Hydrogels Incorporating Clove Oil‐Loaded Mesoporous Bioactive Glass Nanoparticles: A Promising Strategy for Enhanced Bone Regeneration

open access: yesMacromolecular Bioscience, EarlyView.
A novel injectable hydrogel composed of alginate–gelatin–xanthan gum incorporating clove oil (CLV)‐loaded mesoporous bioactive glass nanoparticles is developed. The system demonstrates enhanced antioxidant and antibacterial activity, increased Young's modulus, and good injectability.
Andrada‐Ioana Damian‐Buda   +3 more
wiley   +1 more source

Overactivation of NF-kB pathway can induce apoptosis by down-regulating glycolysis in human degenerative nucleus pulposus cells

open access: yesHeliyon
Intervertebral disc herniation, a prevalent condition in spinal surgery that frequently results in low back pain and lower limb dysfunction, significantly impacting patients' quality of life.
Pan Tang, Bo Liu
doaj   +1 more source

Development of a Grasshopper‐Leg‐Inspired Back‐Type Exoskeleton for the Reduction of Muscle Activation During Stoop Activities

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Farmers frequently suffer from musculoskeletal disorders, particularly lower back pain (LBP), mainly due to occupational ergonomic factors such as repetitive stooping and lifting. This study proposes using an exoskeleton to reduce LBP risk by providing external torque to the hip joints.
Dang Khanh Linh Le, Wei Chih Lin
wiley   +1 more source

Evaluation of Intervertebral Disc Space Width Between 10th and 11th Thoracic Vertebrae in Cats Using Radiography and Magnetic Resonance Imaging

open access: yesVeterinary Medicine and Science
Background It is well known that the T10–T11 intervertebral disc space is usually narrower than the adjacent intervertebral disc spaces in most dogs.
Jiwon Kim   +4 more
doaj   +1 more source

Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell-Based Regeneration. [PDF]

open access: yesJOR Spine
Intervertebral disc degeneration (IDD) is a multifactorial condition underpinned by complex molecular mechanisms. This review highlights advances in RNA sequencing and multi‐omics approaches that have elucidated gene regulatory networks, cellular heterogeneity, and progenitor cell dynamics in the nucleus pulposus.
Stirnimann A   +3 more
europepmc   +2 more sources

MRI Evaluation of Lumbar Disc Degenerative Disease [PDF]

open access: yes, 2015
Introduction: Lower back pain secondary to degenerative disc disease is a condition that affects young to middle-aged persons with peak incidence at approximately 40 y.
Mehta, Chetan   +3 more
core   +2 more sources

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

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