Results 101 to 110 of about 52,505 (294)

Sauteur d'Alfort rabbit‐like locomotory disturbances and eye disorders in two pet rabbits—‘handstand rabbits’

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract Homozygous sauteur d'Alfort rabbits have a splicing‐site mutation in the RAR‐related orphan receptor B (RORB) gene that causes changes in their locomotion. These rabbits sometimes walk on their thoracic limbs, especially at higher speeds. They also experience additional abnormalities, including eye alterations such as blindness due to retinal ...
Kerstin Müller   +4 more
wiley   +1 more source

Vertebral canine myxosarcoma with neurological signs treated by vertebroplasty and radiotherapy (in a dog)

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract Canine myxosarcomas are an uncommon group of tumours, with therapeutic modalities still under research. This case report describes a vertebral myxosarcoma in a 5‐year‐old, mixed‐breed dog causing pelvic limb ataxia. Diagnostic modalities included computed tomography and histopathology.
Flavie Deschildre   +4 more
wiley   +1 more source

Deep Learning Approach for Automated Estimation of 3D Vertebral Orientation of the Lumbar Spine

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Lumbar degenerative disc diseases constitute a major contributor to lower back pain. In pursuit of an enhanced understanding of lumbar degenerative pathology and the development of more effective treatment modalities, the application of precise measurement techniques for lumbar segment kinematics is imperative.
Nanfang Xu   +14 more
wiley   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

open access: yesAging Cell, EarlyView.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang   +6 more
wiley   +1 more source

Review of the tetrapod skull–neck boundary: implications for the evolution of the atlas–axis complex

open access: yesBiological Reviews, EarlyView.
ABSTRACT This review describes variation in modern and fossil occiput–atlas–axis complex anatomy of total group Tetrapoda with the aim of documenting the range of structural variation throughout their evolutionary history to establish grounds for comparison of the complex between tetrapod clades.
Dana E. Korneisel, Hillary C. Maddin
wiley   +1 more source

Targeting FABP4 to Inhibit AGEs‐RAGE/NF‐κB Signalling Effectively Ameliorates Nucleus Pulposus Dysfunction and Angiogenesis in Obesity‐Related Intervertebral Disc Degeneration

open access: yesCell Proliferation, EarlyView.
Obesity promotes the progression of intervertebral disc degeneration (IVDD) through the mTORC1/FABP4 axis. Targeting FABP4 effectively ameliorates nucleus pulposus dysfunction and angiogenesis in obesity‐related IVDD. ABSTRACT Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic ...
Lin Han   +8 more
wiley   +1 more source

Machine learning and single-cell analysis identify the mitophagy-associated gene TOMM22 as a potential diagnostic biomarker for intervertebral disc degeneration

open access: yesHeliyon
Background: Mitophagy selectively eliminates potentially cytotoxic and damaged mitochondria and effectively prevents excessive cytotoxicity from damaged mitochondria, thereby attenuating inflammatory and oxidative responses.
Yinghao Wu   +7 more
doaj  

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