Results 121 to 130 of about 31,985 (192)

Discitis in Children: A 10‐Year Retrospective Review in a Tertiary Pediatric Center

Health Science Reports, Volume 8, Issue 6, June 2025.
Sara Farah, Seilesh Kadambari, Delane Shingadia   +2 more
wiley   +1 more source

Human Disc Degeneration Is Accompanied by a Loss of Anterior Annulus Fibrosus Interlamellar Matrix Integrity as Assessed by Peel Tests

JOR SPINE, Volume 8, Issue 2, June 2025.
Disc degeneration (DD) is associated with reduced mechanical integrity of the interlamellar matrix (ILM) in the annulus fibrosus (AF), as demonstrated by significantly lower Peel Stiffness, Peel Strength, Peel Toughness, and Standard Deviation of the Peel Stress in the Peel Region in DD samples compared to non‐DD samples.
Manmeet S. Dhiman, Mohammed A. Salaam, Taylor J. Bader, Fred Nicholls, W. Bradley Jacobs, Kenneth C. Thomas, Jacques Bouchard, Paul T. Salo, David A. Hart, Ganesh Swamy, Neil A. Duncan   +10 more
wiley   +1 more source

Fundamentals of intervertebral disc degeneration and related discogenic pain. [PDF]

World J Orthop
Peng BG.
europepmc   +1 more source

Nanomedicine Approaches for Intervertebral Disc Regeneration: From Bench to Bedside. [PDF]

Pharmaceutics
Ding Y, Li F, Wang Y, Pan W, Fu X, Tan S.   +5 more
europepmc   +1 more source

Intervertebral Lumbar Spine Kinematics in Chronic Low Back Pain Patients Measured Using Biplane Radiography

JOR SPINE, Volume 8, Issue 2, June 2025.
This study comprehensively characterized dynamic lumbar spine kinematics during active flexion/extension and lateral bending under physiologic loading in individuals with cLBP. The results demonstrate the heterogeneity in lumbar spine intervertebral kinematics in individuals with cLBP.
William Anderst, C. James Kim, Kevin M. Bell, Tom Gale, Cate Gray, Carol M. Greco, Clarissa LeVasseur, Gina McKernan, Sabreen Megherhi, Charity G. Patterson, Sara R. Piva, Caroline Pellegrini, Michael J. Schneider, Joseph Shoemaker, Patrick Smith, Nam V. Vo, Gwendolyn A. Sowa   +16 more
wiley   +1 more source

Unveiling the role of TCF19 in intervertebral disc degeneration with single-cell and bulk RNA sequencing. [PDF]

Sci Rep
He X, Wu L, Zhou H.
europepmc   +1 more source

TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model

JOR SPINE, Volume 8, Issue 2, June 2025.
TNFα receptor‐specific signaling is important in rat IVDD in vivo and in vitro. TNFR1 inhibition was more effective with small molecules than with blocking antibodies. Low levels of TNFR2 in rat AF and NP cells, and the lack of efficacy of TNFR2‐activator Atsttrin, suggest that native AF and NP cells have little capacity for TNFR2‐dependent IVD repair.
Timothy D. Jacobsen, S. Olga Yiantsos, Jennifer Gansau, James Meyers, Damien Laudier, James C. Iatridis   +5 more
wiley   +1 more source

Pathomechanics of Early-Stage Lumbar Intervertebral Disc Degradation Leading to Discogenic Pain-A Narrative Review. [PDF]

Bioengineering (Basel)
Hedman T, Rogers A.
europepmc   +1 more source

Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear‐Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes

JOR SPINE, Volume 8, Issue 2, June 2025.
We examined the associations between fatty infiltration of the lumbar multifidus muscle and clinical outcomes (pain intensity and disability) in people with chronic nonspecific low back pain after controlling for various confounders like demographics, fear‐avoidance beliefs, insomnia, and spinal degenerative phenotypes.
Sabina M. Pinto, Jason P. Y. Cheung, Dino Samartzis, Jaro Karppinen, Yong‐Ping Zheng, Marco Y. C. Pang, Maryse Fortin, Arnold Y. L. Wong   +7 more
wiley   +1 more source