Results 121 to 130 of about 92,764 (319)

Modeling of Degenerative-Dystrophic Changes in the Lumbar Spine Intervertebral Disc in Experiment

open access: yesActa Biomedica Scientifica, 2019
The paper presents an experimental model of the development of degenerative-dystrophic processes in the intervertebral disc at LVI - St level, worked out by specialists of Irkutsk Scientific Centre of Surgery and Traumatology.
O. A. Goldberg   +3 more
doaj   +1 more source

A method of localization and segmentation of intervertebral discs in spine MRI based on Gabor filter bank [PDF]

open access: gold, 2016
Zhu Xin-jian   +6 more
openalex   +1 more source

Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT

open access: diamond, 2021
Martin Wilby   +18 more
openalex   +2 more sources

Nanozyme‐Integrated 3D‐Printed Gradient Scaffold Rescues Redox Homeostasis for Enhanced Osteochondral Repair

open access: yesSmall Structures, EarlyView.
This work presents a novel 3D‐printed gradient scaffold for osteochondral repair. The implant features distinct layers, each designed for a specific therapeutic role: a cartilage layer protects tissue and a bone layer promotes regeneration. In vivo experiments confirm the scaffold's effectiveness, demonstrating its dual ability to maintain chondrocyte ...
Chuan Hu   +7 more
wiley   +1 more source

Protective Effect of Polygonatum sibiricum Polysaccharides on Apoptosis, Inflammation, and Oxidative Stress in Nucleus Pulposus Cells of Rats with the Degeneration of the Intervertebral Disc

open access: yesInternational Journal of Polymer Science, 2019
Objective. Polygonatum sibiricum polysaccharide (PSP) has antioxidant activity, immune enhancement, and other biological properties. However, the effect of PSP on intervertebral disc degeneration has not been reported.
Zhaohui Zhai   +3 more
doaj   +1 more source

Axial T2* mapping in intervertebral discs: a new technique for assessment of intervertebral disc degeneration [PDF]

open access: yes, 2018
Objectives: To demonstrate the potential benefits of biochemical axial T2* mapping of intervertebral discs (IVDs) regarding the detection and grading of early stages of degenerative disc disease using 1.5-Tesla magnetic resonance imaging (MRI) in a ...
Benneker, Lorin   +5 more
core  

SYNJ2BP ameliorates intervertebral disc degeneration by facilitating mitochondria-associated endoplasmic reticulum membrane formation and mitochondrial Zn2+ homeostasis

open access: hybrid, 2023
Yu Song   +12 more
openalex   +1 more source

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

open access: yesSmall Structures, EarlyView.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee   +4 more
wiley   +1 more source

The Role of miR-31-5p in the Development of Intervertebral Disc Degeneration and Its Therapeutic Potential

open access: gold, 2021
Yong Zhou   +5 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

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