Results 11 to 20 of about 92,764 (319)

Equine cervical intervertebral disc degeneration is associated with location and MRI features [PDF]

open access: yes, 2019
Morphology of the equine cervical intervertebral disc is different from that in humans and small companion animals and published imaging data are scarcely available.
Back, Willem   +6 more
core   +1 more source

Mechanotransduction in intervertebral discs [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2014
AbstractMechanotransduction plays a critical role in intracellular functioning—it allows cells to translate external physical forces into internal biochemical activities, thereby affecting processes ranging from proliferation and apoptosis to gene expression and protein synthesis in a complex web of interactions and reactions.
Tsai, Tsung-Ting   +3 more
openaire   +2 more sources

Prolapsed intervertebral disc [PDF]

open access: yesBMJ, 2008
Prolapsed intervertebral disc is common—it is seen in up to a quarter of magnetic resonance scans and can be detected even in asymptomatic adults.1 Disc prolapse is genetically driven—twin studies indicate that at least 60% of the variance can be explained on genetic grounds and not by the commonly assumed environmental factors (work, trauma, exposure ...
openaire   +2 more sources

Protective role of the alpha-1-antitrypsin in intervertebral disc degeneration

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Intervertebral disc degeneration is a complex disease with high prevalence. It suggests that cell death, senescence, and extracellular matrix degradation are involved in the pathogenesis. Alpha-1 antitrypsin (AAT), a serine protease inhibitor,
Weikun Liu, Yanfu Wang
doaj   +1 more source

Pressure distributions inside intervertebral discs under unilateral pedicle screw fixation in a porcine spine model

open access: yesJournal of Orthopaedic Surgery and Research, 2018
Background Little data are available regarding the effects of pedicle screws on the intervertebral disc stress for different spinal segments. The aim of this study was to analyze the intervertebral disc stress in response to the placement of pedicle ...
Zhao Meng   +5 more
doaj   +1 more source

Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]

open access: yes, 2016
Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
core   +2 more sources

Effect of sIL-13Rα2-Fc on the progression of rat tail intervertebral disc degeneration

open access: yesJournal of Orthopaedic Surgery and Research, 2019
Background The incidence of degenerative disc disease caused by intervertebral disc injury is increasing annually, seriously affecting the quality of life of patients and increasing the disease burden on society.
Xin Wang   +7 more
doaj   +1 more source

Methanolysis of the Intervertebral Disc

open access: yesClinical Chemistry, 1967
Abstract Methanolysis of intervertebral disc samples at 60° was largely hydrolysis as shown by the absence of methylated derivatives on chromatograms of the reaction products. Extent of the reaction increased with acid strength; the products were the same.
D, Chan, E W, Hull, M, Fields, E, McNall
openaire   +2 more sources

MiR-532 downregulation of the Wnt/β-catenin signaling via targeting Bcl-9 and induced human intervertebral disc nucleus pulposus cells apoptosis

open access: yesJournal of Pharmacological Sciences, 2018
Objective: Intervertebral disc degeneration was characterized with aberrant intervertebral disc nucleus pulposus cells apoptosis. MiR-532 was reported to be up-regulated in the patients with intervertebral disc degeneration.
Zeyu Sun   +3 more
doaj   +1 more source

Identification of Key Modules and Hub Genes of Annulus Fibrosus in Intervertebral Disc Degeneration

open access: yesFrontiers in Genetics, 2021
Background: Intervertebral disc degeneration impairs the quality of patients lives. Even though there has been development of many therapeutic strategies, most of them remain unsatisfactory due to the limited understanding of the mechanisms that underlie
Hantao Wang   +5 more
doaj   +1 more source

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