Results 91 to 100 of about 40,769 (270)

Structure-function relationships at the human spinal disc-vertebra interface. [PDF]

, 2018
Damage at the intervertebral disc-vertebra interface associates with back pain and disc herniation. However, the structural and biomechanical properties of the disc-vertebra interface remain underexplored.
Adams, Adams, Adams, Adams, Arce, Ayache, Bae, Balkovec, Benjamin, Brown, DeLucca, DeLucca, Fields, Fields, Genin, Green, Guerin, Ho, Hulme, Inoue, Jazrawi, Lama, Law, Lecompte, Liu, Nosikova, Paietta, Raghupathy, Rajasekaran, Roberts, Roberts, Rodrigues, Silva, Tanaka, Thomopoulos, Thomopoulos, Thompson, Thompson, Wade, Wagermaier, Wang, Wang, Willburger, Yoshiaki   +43 more
core   +1 more source

Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives We propose a non‐destructive laser method that uses controlled thermomechanical action to treat degenerative cartilage changes. The technique aims to reduce pain, offers a minimally invasive option for early‐ to mid‐stage degeneration, and lessens the need for joint replacement.
Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol   +6 more
wiley   +1 more source

An investigation into the effectiveness of collagenase for the percutaneous discolysis of thoracolumbar intervertebral discs in the dog : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University [PDF]

, 1993
This investigation compared the effectiveness of chemonucleolysis with 500 units of collagenase, to lateral fenestration of the thoracolumbar intervertebral discs of the non-chondrodystrophoid dog.
Bray, Jonathan Peter
core  

Intervertebral disc characterization by shear wave elastography: an in-vitro preliminary study [PDF]

, 2014
Patient-specific numerical simulation of the spine is a useful tool both in clinic and research. While geometrical personalization of the spine is no more an issue, thanks to recent technological advances, non-invasive personalization of soft tissue’s ...
BONNEAU, Dominique, DUBOIS, Guillaume, DUBOUSSET, Jean, GENNISSON, Jean-Luc, ROUCH, Philippe, SKALLI, Wafa, TANTER, Mickael, VERGARI, Claudio, VERGARI, Claudio   +8 more
core   +4 more sources

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

Small Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li, Qingzheng Zhang, Zongtai Liu, Weiguo Xu, Changfeng Fu, Jianxun Ding   +5 more
wiley   +1 more source

Biomechanical study of intervertebral disc degeneration

, 2023
Degeneration and age affect the biomechanics of the intervertebral disc, by reducing its stiffness, flexibility and shock absorption capacities against daily movement and spinal load. The biomechanical characterization of intervertebral discs is achieved by conducting mechanical testing to vertebra-disc-vertebra segments and applying axial, shear, bend
openaire   +4 more sources

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

Small Science, EarlyView.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li, Xudong Xie, Chong Ding, Shengming Zhang, Liangcong Hu, Bobin Mi, Mengfei Liu, Guohui Liu   +7 more
wiley   +1 more source

Occurrence and Regional Distribution of TRAIL and DR5 on Temporomandibular Joint Discs: Comparison of Disc Derangement with and without Reduction [PDF]

, 2010
Background Tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is an apoptosis-inducing member of the TNF gene family which triggers apoptotic signals by interaction with its receptors.
Almeida, Luis Eduardo, Leonardi, Rosalia, Loreto, Carla, Trevilatto, Paula C.   +3 more
core   +1 more source

Effect of screening abdominal ultrasound examination on the decision to pursue advanced diagnostic tests and treatment in dogs with neurologic disease. [PDF]

, 2015
BackgroundAbdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis.ObjectivesDescribe the type and frequency of abnormalities found by AUS in ...
Blair, WH, Chen, RX, Sturges, BK, Taylor, SL, Tong, NM, Zwingenberger, AL   +5 more
core   +1 more source

Dual‐Lineage Chondrocyte‐Like Cells in the Nucleus Pulposus of Aging Intervertebral Discs Are Accelerated by Hedgehog Signaling Inactivation

Aging Cell, EarlyView.
During intervertebral disc degeneration, notochord‐derived nucleus pulposus cells progressively transdifferentiate into Krt19+ chondrocyte‐like cells (CLCs) and Krt19− CLCs, which are eventually replaced by Krt19− CLCs from non‐notochordal Gli1+ progenitors.
Lei Zhang, Chunmei Xiu, Hongji You, Jianquan Chen   +3 more
wiley   +1 more source