Unveiling key genes for intervertebral disc degeneration prediction and potential drug discovery. [PDF]
Li TJ, Wang YS, Lan BB, Liu JW.
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Mendelian randomization analysis identifies HLA-A and AP2M1 as genetic biomarkers linked to immune-endocytic crosstalk in intervertebral disc degeneration. [PDF]
Tian Y, Bai X, Han N, Wang C, Liu J.
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The role of nucleus pulposus progenitor cells in intervertebral disc degeneration and regeneration. [PDF]
Wang P +5 more
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Astragalus Polysaccharide Enhances O-GlcNAcylation Through OGT to Improve Intervertebral Disc Degeneration in Rats. [PDF]
Tan H +5 more
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Bioactive metabolites of botanical drugs in the treatment of intervertebral disc degeneration-a review of promising therapeutic candidate. [PDF]
Qi L, Fan X, Sun J.
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Screening and identification of differentially expressed miRNA and mRNA for intervertebral disc degeneration on bioinformatics. [PDF]
Yan J +6 more
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Correction to 'Integrating Bulk RNA and Single-Cell RNA Sequencing Identifies and Validates Lactylation-Related Signatures for Intervertebral Disc Degeneration'. [PDF]
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Pathomechanism of intervertebral disc degeneration
AbstractIntervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and longālasting treatments for IDD are still lacking.
Takeshi Oichi +2 more
exaly +4 more sources
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Genetics of Intervertebral Disc Degeneration
Current Osteoporosis Reports, 2023Intervertebral disc degeneration is a contributor to chronic back pain. While a part of the natural aging process, early or rapid intervertebral disc degeneration is highly heritable. In this review, we summarize recent progress towards unraveling the genetics associated with this degenerative process.Use of large cohorts of patient data to conduct ...
David C. Ou-Yang +2 more
openaire +2 more sources

