Results 51 to 60 of about 14,963 (141)

Chronic Unpredictable Stress Induces Intervertebral Disk Cell Apoptosis and Degeneration

Global Spine Journal, 2012
Introduction Animal model was used to study the effects of chronic unpredictable stress (CUS) on the intervertebral disk (IVD). Stress is a predictor for low back disability in persons with earlier low back pain (LBP) and LBP is most common in the early ...
H. Reihani Kermani, H. Hobubati, S. Esmaeili Mahani, M. Assadi Shekari   +3 more
doaj   +1 more source

Influence of mononuclear cell therapy on disc degeneration in rabbits

Revista Brasileira de Ortopedia
OBJECTIVE: The objective of this research was to evaluate the influence of autologous mononuclear stem cells injections on histological changes of collagen in the fibrous annulus of the intervertebral disk after experimental injury.
Rodrigo Caldonazzo Fávaro, André de Oliveira Arruda, Luiz Roberto Gomes Vialle, Emiliano Neves Vialle   +3 more
doaj   +1 more source

A cross-sectional study: serum CCL3/MIP-1α levels may reflect lumbar intervertebral disk degeneration in Han Chinese people

Journal of Pain Research, 2018
Yi-Li Zhang,1,2,* Bei Li,1,2,* Zeng-Huan Zhou1 1School of Public Health, Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China; 2School of Health Services Management, Southern Medical University, Guangzhou ...
Zhang YL, Li B, Zhou ZH
doaj  

On the suitability of additively manufactured gyroid structures and their potential use as intervertebral disk replacement - a feasibility study

Frontiers in Bioengineering and Biotechnology
IntroductionIntervertebral disk degeneration is a growing problem in our society. The degeneration of the intervertebral disk leads to back pain and in some cases to a herniated disk.
Valentin Gross, Valentin Gross, Sergej Zankovic, Bernd Rolauffs, Dirk Velten, Hagen Schmal, Michael Seidenstuecker, Michael Seidenstuecker   +7 more
doaj   +1 more source

Effect of a novel compressible artificial disk on biomechanical performance of cervical spine: A finite element study

Advances in Mechanical Engineering, 2015
Spinal interbody fusion is the most common surgery for treatment of disk degeneration, but the increased stress on adjacent level has been noted.
Jou-Wen Chen, Wen-Chuan Chen, Yu-Shu Lai, Chia-Ming Chang, Shih-Tien Wang   +4 more
doaj   +1 more source

Mechanical Basis of Lumbar Intervertebral Disk Degeneration

Indian Spine Journal
Abstract The etiology of degenerative disk disease (DDD) is multifactorial. Among the various factors, mechanical processes contributing to endplate or discal injuries have been discussed as the initiating events in the degenerative cascade. DDD encompasses the multitudinous changes undergone by the different structures of the spinal segment,
Sathish Muthu, Vibhu Krishnan Visawanathan, Girinivasan Chellamuthu   +2 more
openaire   +1 more source

Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study

JOR Spine, 2018
Mechanical loading is inherently related to the function and degeneration of the intervertebral disc. We present a series of experiments aimed at measuring the effect of a loading/unloading cycle of the intervertebral disc on the mechanical properties of
Steven V. Beekmans, Kaj S. Emanuel, Theodoor H. Smit, Davide Iannuzzi   +3 more
doaj   +1 more source

Micromorphological Investigations of Intervertebral Disk Degeneration using Electron Microscopy

Global Spine Journal, 2012
Introduction Intervertebral disk (ID) degeneration can be distinguished by various changes in the tissue structure like delamination and crack formation of the collagenous matrix as well as cellular changes like cell aging and variances in the amount and
A. Friedmann, S. Schwan, F. Goehre, A. Heilmann, H. J. Meisel   +4 more
doaj   +1 more source

Degenerative Disc Disease: A Review of Cell Technologies and Stem Cell Therapy

Iranian Journal of Neurosurgery, 2016
Background & Aim: Low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. Although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration.
Kaveh Haddadi
doaj  

Current status and development direction of immunomodulatory therapy for intervertebral disk degeneration. [PDF]

Front Med (Lausanne), 2023
Gao Y, Chen X, Zheng G, Lin M, Zhou H, Zhang X.   +5 more
europepmc   +1 more source