Results 81 to 90 of about 16,112 (151)

Staged Lateral Lumbar Interbody Fusion Targeting Driver and Compensatory Structural Segments for Adult Degenerative Scoliosis: A Novel Strategy and Early Outcomes

Orthopaedic Surgery, EarlyView.
Targeting driver and structural vertebrae via LLIF is an effective, minimally invasive strategy for ADS. It offers substantial deformity correction, symptom relief, and progressive postoperative self‐correction while significantly reducing surgical trauma compared to traditional long‐segment fusions.
Tianyong Wen, Liukun Xu, Peng Lu, Yang Zhang, Wei Ji, Yang Zheng, Zhicheng Zhang, Tiansheng Sun   +7 more
wiley   +1 more source

Micromorphological Investigations of Intervertebral Disk Degeneration using Electron Microscopy

Global Spine Journal, 2012
Introduction Intervertebral disk (ID) degeneration can be distinguished by various changes in the tissue structure like delamination and crack formation of the collagenous matrix as well as cellular changes like cell aging and variances in the amount and
A. Friedmann, S. Schwan, F. Goehre, A. Heilmann, H. J. Meisel   +4 more
doaj   +1 more source

Effect of Keeping Caspar Retractor During Prestige LP Cervical Disc Implantation on Intra‐ and Postoperative Outcomes

Orthopaedic Surgery, EarlyView.
This study evaluated the effect of retaining the Caspar retractor during Prestige LP implantation in cervical disc arthroplasty (CDA). Although the manufacturer recommends removal, removal caused vertebral instability during endplate drilling/cutting. Retaining the retractor reduced angle fluctuations, implantation time, and fluoroscopy usage, though ...
Xiaoqiang Zhao, Xiao Yang, Minghe Yao, Kangkang Huang, Tingkui Wu, Shihao Chen, Yi Deng, Hao Liu, Beiyu Wang   +8 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Biomimetic Microstructural Materials for Intervertebral Disk Degeneration Repair

Small Structures
The intervertebral disks (IVD) serve as shock absorbers in the spine. As the largest avascular tissue in the human body, it has a limited capacity for regeneration.
Ang Li, Hui Yuan, Feng Cai, Juan Wang, Zehao Chen, Xiaohu Li, Hongze Chang, Wenguo Cui, Xiaodong Liu   +8 more
doaj   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Degenerative Disc Disease: A Review of Cell Technologies and Stem Cell Therapy

Iranian Journal of Neurosurgery, 2016
Background & Aim: Low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. Although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration.
Kaveh Haddadi
doaj  

Cerebrospinal Fluid Creatine Kinase as a Biomarker in Dogs With Neurologic Disease: A Multivariate Analysis to Guide Future Directions

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Creatine kinase (CK) is typically associated with skeletal muscle injury, but elevated CK in blood or cerebrospinal fluid (CSF) may also be reflective of central nervous system damage. Previous research has therefore explored the role of CK as a biomarker of neurologic disease in veterinary patients.
Taylor A. Hanson, Michael F. Rosser, Benjamin Blair, Graeme M. Doodnaught, Chandler C. Carter, Anne M. Barger, Kari Foss   +6 more
wiley   +1 more source

Delays to fracture stabilization and the effect on postoperative outcomes: A retrospective cohort study of 211 canine humeral condylar fractures

Veterinary Surgery, EarlyView.
Abstract Objective To investigate the effect of surgical delay on radiographic and patient outcomes following canine humeral condylar fracture stabilization. Study design Retrospective observational cohort study. Sample population A total of 211humeral condylar fractures (204 dogs).
Daniel Low, Maria Manou, Scott Rutherford   +2 more
wiley   +1 more source

The role of fenestration in acute canine thoracolumbar intervertebral disc extrusion: Part 2—The biological and biomechanical effects of fenestration

Veterinary Surgery, EarlyView.
Abstract Background Prophylactic fenestration is widely performed to prevent recurrence of canine acute thoracolumbar intervertebral disc extrusion (IVDE); however, there is a paucity of specific data regarding the biological and biomechanical effect of this procedure on the intervertebral disc and vertebral column.
James D. Crowley, Paul Freeman, William R. Walsh   +2 more
wiley   +1 more source