Results 91 to 100 of about 16,112 (151)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Mechanobiology of MicroRNAs in Intervertebral Disk Degeneration. [PDF]

J Spine Res Surg, 2023
Supra R, Agrawal DK.
europepmc   +1 more source

Diffuse Idiopathic Skeletal Hyperostosis (DISH) With Cervical Myelopathy: A Case Report From Sudan

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Diffuse idiopathic skeletal hyperostosis (DISH) is a non‐inflammatory condition characterized by ossification of spinal ligaments, commonly affecting elderly individuals. While often asymptomatic, it may present severe neurological deficits due to spinal cord compression.
Elham Abdalla, Mohammed Alfatih, Mohammed Alssir MohammedAhmed, Amel Siddig, Hassan Zeyada   +4 more
wiley   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen, Xiwen Wang, Xiuping Wang, Na Lin, Wenjie Wang, Ruiqi Fu, Yutong Wu, Yi Liu, Hengwei Liu   +8 more
wiley   +1 more source

Identification and Experimental Validation of PANoptosis Key Genes for Constructing a PANoptosis Risk Diagnostic Model in Intervertebral Disc Degeneration

The Journal of Gene Medicine, Volume 28, Issue 10, October 2026.
This study identified seven PANoptosis key genes (ACSBG1, FXYD1, APCS, CEACAM1, ERAP2, ABL1, and FZD3) in intervertebral disc degeneration (IDD) through integrated bioinformatics analysis of GEO datasets. Using machine learning algorithms (RF, SVM, XGB, and GLM), a PANoptosis risk diagnostic model was constructed and validated.
Kui Deng, Xia Lan, WenZhao Chen, LiuXue Du, JiangWei Chen   +4 more
wiley   +1 more source

Current status and development direction of immunomodulatory therapy for intervertebral disk degeneration. [PDF]

Front Med (Lausanne), 2023
Gao Y, Chen X, Zheng G, Lin M, Zhou H, Zhang X.   +5 more
europepmc   +1 more source

What Is Your Diagnosis? Leukocytosis With Abnormal WDF and WNR Scattergrams From the Sysmex XN‐1000V in a Dog

Veterinary Clinical Pathology, EarlyView.
Javier Martínez‐Caro, Marta Lemos, Josep Pastor   +2 more
wiley   +1 more source

Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration. [PDF]

Int J Mol Sci, 2023
Shnayder NA, Ashhotov AV, Trefilova VV, Nurgaliev ZA, Novitsky MA, Vaiman EE, Petrova MM, Nasyrova RF.   +7 more
europepmc   +1 more source

Retracted: GINS2 Is Downregulated in Peripheral Blood of Patients with Intervertebral Disk Degeneration and Promotes Proliferation and Migration of Nucleus Pulposus Cells. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Does Calcium Phosphate Cement Kyphoplasty Cause Intervertebral Disk Degeneration in Adolescents? [PDF]

Cartilage, 2022
Tschauner S, Singer G, Weitzer CU, Castellani C, Till H, Sorantin E, Wegmann H.   +6 more
europepmc   +1 more source