Results 101 to 110 of about 14,963 (141)

Roles of Chemokines in Intervertebral Disk Degeneration

Current Pain and Headache Reports, 2023
Intervertebral disc degeneration is the primary etiology of low back pain and radicular pain. This review examines the roles of crucial chemokines in different stages of degenerative disc disease, along with interventions targeting chemokine function to mitigate disc degeneration.The release of chemokines from degenerated discs facilitates the ...
Pengfei, Xue, Yi, Wang, Long, Lv, Dongming, Wang, Yuntao, Wang   +4 more
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Lumbar Intervertebral Disk Degeneration

Orthopedic Clinics of North America, 2011
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Samartzis, D, Cheung, KMC
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A validated new classification for intervertebral disk degeneration

Khirurgiya. Zhurnal im. N.I. Pirogova, 2022
To develop a new validated classification of intervertebral disc degeneration.A retrospective observational single-center study included medical records of patients with and without degenerative disease of lumbar intervertebral discs. The interval values of apparent diffusion coefficient (ADC) of intervertebral discs were grouped into degeneration ...
I.A. Stepanov, V.A. Beloborodov, V.A. Sorokovikov   +2 more
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Lumbar Intervertebral Disk Degeneration in Athletes

The American Journal of Sports Medicine, 2008
Background Several studies have reported that physical loading related to competitive sports activities is associated with lumbar intervertebral disk degeneration. However, the association between types of sports activities and disk degeneration has not been clarified.
Mika, Hangai, Koji, Kaneoka, Shiro, Hinotsu, Ken, Shimizu, Yu, Okubo, Shumpei, Miyakawa, Naoki, Mukai, Masataka, Sakane, Naoyuki, Ochiai   +8 more
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Bacteriology of Degenerated Lumbar Intervertebral Disks

Journal of Spinal Disorders & Techniques, 2012
A prospective microbiological analysis of intervertebral disk material in surgically treated patients presenting lumbar disk degeneration.To determine the prevalence and species of bacteria in degenerated lumbar disks, their eventual role in the pathophysiology, and the possible influence of risk factors.Intervertebral disk degeneration results from ...
Joseph, Arndt, Yann Philippe, Charles, Christelle, Koebel, Ioan, Bogorin, Jean-Paul, Steib   +4 more
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Interleukin-1β in intervertebral disk degeneration

Clinica Chimica Acta, 2015
Intervertebral disk degeneration (IDD) is the most common diagnosis in patients with low back pain, a main cause of musculoskeletal disability in the world. Interleukin-1 (IL-1) β is the most important member of the IL-1 family, and has a strong pro-inflammatory activity by stimulating the secretion of multiple pro-inflammatory mediators.
Wei, Yang, Xiao-Hua, Yu, Cheng, Wang, Wen-Si, He, Shu-Jun, Zhang, Yi-Guo, Yan, Jian, Zhang, Yong-Xiao, Xiang, Wen-Jun, Wang   +8 more
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Intervertebral Disk Degeneration and Emerging Biologic Treatments

American Academy of Orthopaedic Surgeon, 2011
Although understanding of the biologic basis of intervertebral disk (IVD) degeneration is rapidly advancing, the unique IVD environment presents challenges to the development and delivery of biologic treatments. Acceleration of cellular senescence and apoptosis in degenerative IVDs and the depletion of matrix proteins have prompted the development of ...
Christopher K, Kepler, D Greg, Anderson, Chadi, Tannoury, Ravi K, Ponnappan   +3 more
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IMAGING OF LUMBAR INTERVERTEBRAL DISK DEGENERATION AND AGING, EXCLUDING DISK HERNIATIONS

Radiologic Clinics of North America, 2000
With the advent of CT and MR imaging, physicians have been able to complement their clinical diagnosis of the cause of low back pain with a detailed in vivo image of the structure and soft tissues of the spine. At the same time, there has been an increasing realization that information about morphology alone is not enough to make a definitive diagnosis.
J G, Jarvik, R A, Deyo
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Correlation between T2 relaxation time and intervertebral disk degeneration

Skeletal Radiology, 2011
Magnetic resonance T2 mapping allows for the quantification of water and proteoglycan content within tissues and can be used to detect early cartilage abnormalities as well as to track the response to therapy. The goal of the present study was to use T2 mapping to quantify intervertebral disk water content according to the Pfirrmann classification.This
Hiroyuki, Takashima, Tsuneo, Takebayashi, Mitsunori, Yoshimoto, Yoshinori, Terashima, Hajime, Tsuda, Kazunori, Ida, Toshihiko, Yamashita   +6 more
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Classification of Intervertebral Disk Degeneration with Axial T2 Mapping

American Journal of Roentgenology, 2007
The aim of this study was to establish an MRI classification system for intervertebral disks using axial T2 mapping, with a special focus on evaluating early degenerative intervertebral disks.Twenty-nine healthy volunteers (19 men, 10 women; age range, 20-44 years; mean age, 31.8 years) were studied, and axial T2 mapping was performed for the L3-L4, L4-
Atsuya, Watanabe, Lorin M, Benneker, Chris, Boesch, Tomoko, Watanabe, Takayuki, Obata, Suzanne E, Anderson   +5 more
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