Intestinal Absorption of Fructose [PDF]
Annual Review of Nutrition, 2018 Increased understanding of fructose metabolism, which begins with uptake via the intestine, is important because fructose now constitutes a physiologically significant portion of human diets and is associated with increased incidence of certain cancers and metabolic diseases.
Ronaldo P. Ferraris +2 more
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Intestinal Absorption Study: Challenges and Absorption Enhancement Strategies in Improving Oral Drug Delivery. [PDF]
Pharmaceuticals (Basel), 2022 The oral route is the most common and practical means of drug administration, particularly from a patient’s perspective. However, the pharmacokinetic profile of oral drugs depends on the rate of drug absorption through the intestinal wall before entering
Azman M +4 more
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Simultaneous Prediction Method for Intestinal Absorption and Metabolism Using the Mini-Ussing Chamber System [PDF]
Pharmaceutics, 2023 Many evaluation tools for predicting human absorption are well-known for using cultured cell lines such as Caco-2, MDCK, and so on. Since the combinatorial chemistry and high throughput screening system, pharmacological assay, and pharmaceutical ...
Satoshi Kondo, Masateru Miyake
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Journal of Nanobiotechnology, 2021 Background The use of drug nanocarriers to encapsulate drugs for oral administration may become an important strategy in addressing the challenging oral absorption of some drugs.
Shiqi Guo +7 more
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Journal of Lipid Research, 1964 Great progress in understanding the mechanisms of fat absorption by the mammalian intestine has been made in the past decade and a half. In contrast to the contentions of rival theorists of the century before this, it has been possible for many ...
John R. Senior
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Glyceroniosomes for enhanced intestinal absorption of hydrochlorothiazide and lisinopril in their fixed dose combination [PDF]
Scientific ReportsThe objective was to investigate the effect of co-administration of hydrochlorothiazide and lisinopril as fixed dose combination on their intestinal absorption. The scope was extended to enhance intestinal absorption of both drugs.
Aya R. Elbasuony +3 more
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Bilosomes and Niosomes for Enhanced Intestinal Absorption and In Vivo Efficacy of Cytarabine in Treatment of Acute Myeloid Leukemia [PDF]
PharmaceuticalsCytarabine (CTR) is a hydrophilic anticancer drug used to treat leukemia. It suffers from poor permeability and intestinal metabolism, diminishing its oral bioavailability.
Abdelrahman R. Said +4 more
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Effect of luteolin on ceftiofur intestinal absorption: the rational use of Caco-2 monolayer cell model and everted gut sac model [PDF]
Poultry ScienceBackground: The clinical utility of ceftiofur primarily stems from its broad-spectrum antibacterial properties. However, its limited oral bioavailability significantly constrains therapeutic effectiveness.
Ruxia Wang +8 more
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The Intestinal Absorption of Folates [PDF]
Annual Review of Physiology, 2014 The properties of intestinal folate absorption were documented decades ago. However, it was only recently that the proton-coupled folate transporter (PCFT) was identified and its critical role in folate transport across the apical brush-border membrane of the proximal small intestine established by the loss-of-function mutations identified in the PCFT
Rongbao Zhao +3 more
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Progress in Research and Application of Intestinal Absorption Cell Models on Carotenoids [PDF]
Shipin Kexue, 2023 Dietary compounds are crucial in maintaining human physiological functions and preventing diseases, but they can give full play to their functional activities only after being effectively absorbed and utilized by the human body.
WU Fan, CHEN Nan, WU Yuqing, NI Yuanying, WEN Xin
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