Results 11 to 20 of about 368,441 (377)

Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery

open access: yesPharmaceutics, 2022
Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration.
Rong Lu   +4 more
doaj   +1 more source

Application Research Progress of Intestinal Organoids in Nutrient Absorption

open access: yesShipin gongye ke-ji, 2022
The intestinal tract is not only the main part of nutrient digestion and absorption, but also an important immune and endocrine organ. The digestion and absorption of nutrients in the intestine is a crucial factor to achieve their efficient utilization ...
Yaxuan PENG   +7 more
doaj   +1 more source

Intestinal Absorption of Fructose [PDF]

open access: yesAnnual Review of Nutrition, 2018
Increased understanding of fructose metabolism, which begins with uptake via the intestine, is important because fructose now constitutes a physiologically significant portion of human diets and is associated with increased incidence of certain cancers and metabolic diseases.
Ronaldo P. Ferraris   +2 more
openaire   +2 more sources

Drug Absorption Studies: In Situ, In Vitro and In Silico Models [PDF]

open access: yes, 2022
This Book serves to highlight the mechanisms related to the low intestinal drug absorption, the strategies to overcome the obstacles or intestinal drug absorption, and in situ, in vitro, and in silico methodologies to predict to intestinal drug ...

core   +1 more source

Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]

open access: yes, 2015
Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor   +4 more
core   +6 more sources

COMP Report: CPQR technical quality control guidelines for use of positron emission tomography/computed tomography in radiation treatment planning

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Positron emission tomography with x‐ray computed tomography (PET/CT) is increasingly being utilized for radiation treatment planning (RTP). Accurate delivery of RT therefore depends on quality PET/CT data. This study covers quality control (QC) procedures required for PET/CT for diagnostic imaging and incremental QC required for RTP.
Ran Klein   +7 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi   +5 more
wiley   +1 more source

Evaluation of patient doses for routine digital radiography procedures toward establishing an institutional diagnostic reference levels: A case study in Sri Lanka

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract The present study was conducted as part of a comprehensive work to establish National Diagnostic Reference Levels (NDRLs) in Sri Lanka for the first time. DRLs can be used as an effective optimization tool for identifying unusually high or low patient doses during X‐ray examinations.
Sachith Welarathna   +3 more
wiley   +1 more source

A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models [PDF]

open access: yes, 2020
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic homeostasis of this essential trace element. This review summarizes the key aspects of human zinc homeostasis and distribution.
Haase, Hajo, Maares, Maria
core   +1 more source

Training Generative Adversarial Networks for Optical Property Mapping using Synthetic Image Data [PDF]

open access: yesBiomedical Optics Express 2022, 2022
We demonstrate training of a Generative Adversarial Network (GAN) for prediction of optical property maps (scattering and absorption) using spatial frequency domain imaging (SFDI) image data sets generated synthetically with free open-source 3D modelling and rendering software, Blender.
arxiv   +1 more source

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