Results 11 to 20 of about 2,415,912 (381)
Intestinal Absorption of Fructose [PDF]
Annual Review of Nutrition, 2018 Increased understanding of fructose metabolism, which begins with uptake via the intestine, is important because fructose now constitutes a physiologically significant portion of human diets and is associated with increased incidence of certain cancers and metabolic diseases.
Ronaldo P, Ferraris +2 more
openaire +3 more sources
Journal of Nanobiotechnology, 2021 Background The use of drug nanocarriers to encapsulate drugs for oral administration may become an important strategy in addressing the challenging oral absorption of some drugs.
Shiqi Guo +7 more
doaj +2 more sources
A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models [PDF]
Nutrients, 2020 Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic homeostasis of this essential trace element. This review summarizes the key aspects of human zinc homeostasis and distribution.
Haase, Hajo, Maares, Maria
core +2 more sources
Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]
International Journal of Molecular Sciences, 2015 Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor +4 more
core +7 more sources
The Intestinal Absorption of Folates [PDF]
Annual Review of Physiology, 2014 The properties of intestinal folate absorption were documented decades ago. However, it was only recently that the proton-coupled folate transporter (PCFT) was identified and its critical role in folate transport across the apical brush-border membrane of the proximal small intestine established by the loss-of-function mutations identified in the PCFT
Michele, Visentin +3 more
openaire +3 more sources
Intestinal Absorption Study: Challenges and Absorption Enhancement Strategies in Improving Oral Drug Delivery. [PDF]
Pharmaceuticals (Basel), 2022 The oral route is the most common and practical means of drug administration, particularly from a patient’s perspective. However, the pharmacokinetic profile of oral drugs depends on the rate of drug absorption through the intestinal wall before entering
Azman M +4 more
europepmc +2 more sources
Vitamin D-Mediated Regulation of Intestinal Calcium Absorption
Nutrients, 2022 Vitamin D is a critical regulator of calcium and bone homeostasis. While vitamin D has multiple effects on bone and calcium metabolism, the regulation of intestinal calcium (Ca) absorption efficiency is a critical function for vitamin D.
J. Fleet
semanticscholar +1 more source
Cell-Penetrating Peptide-Surface Modified Liposomes to Enhance the Intestinal Absorption of Enoxaparin [PDF]
Pharmaceutical Sciences, 2023 Background: Enoxaparin is low-molecular-weight heparin administered by subcutaneous/intravenous injection. The oral bioavailability of enoxaparin is restricted by its low absorption through the intestine.
Hessam Rostamian +4 more
doaj +1 more source
Mitochondrial reactive oxygen species modify extracellular vesicles secretion rate
FASEB BioAdvances, 2023 Extracellular vesicle (EV) secretion rate is stimulated by hypoxia that causes increased reactive oxygen species (ROS) production by the mitochondrial electron transport chain (ETC) and hypoxia‐induced factor (HIF)‐1 signaling; however, their ...
Mikkel Ø. Nørgård +6 more
doaj +1 more source
Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery
Pharmaceutics, 2022 Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration.
Rong Lu +4 more
doaj +1 more source