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Low zinc status and absorption exist in infants with jejunostomies or ileostomies which persists after intestinal repair. [PDF]
There is very little data regarding trace mineral nutrition in infants with small intestinal ostomies. Here we evaluated 14 infants with jejunal or ileal ostomies to measure their zinc absorption and retention and biochemical zinc and copper status. Zinc
Abrams, Steven A+5 more
core +4 more sources
Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies
Intestinal absorption is a complex process involving the permeability of the epithelial barrier, efflux transporter activity, and intestinal metabolism.
Kazuyoshi Michiba+3 more
doaj +1 more source
Flexural Behavior of Bidirectionally Graded Lattice
An experimental study of the bending behavior of bidirectional body‐centered cubic lattice beams is conducted in comparison to uniform and unidirectional counterparts of electron beam melted SS 316 L. Experimental results are used to develop and validate a finite element model which is subsequently used to conduct parametric studies to assess the ...
Chamini Rodrigo+4 more
wiley +1 more source
Mathematical Modeling of Transport and Degradation of Feedstuffs in the Small Intestine [PDF]
We describe a mathematical modeling of the digestion in the small intestine. The main interest of our work is to consider, at the same time, different aspects of the digestion i.e. the transport of the bolus all along the intestine, feedstuffs degradation according to the enzymes and local physical conditions, and nutrients absorption.
arxiv +1 more source
Prediction of the intestinal absorption of new chemical entities (NCEs) is still difficult, in part because drug efflux transporters, including breast cancer resistance protein (BCRP) and P‐glycoprotein (P‐gp), restrict their intestinal permeability.
Iichiro Kawahara+4 more
doaj +1 more source
The Intestinal Absorption of Folates [PDF]
The properties of intestinal folate absorption were documented decades ago. However, it was only recently that the proton-coupled folate transporter (PCFT) was identified and its critical role in folate transport across the apical brush-border membrane of the proximal small intestine established by the loss-of-function mutations identified in the PCFT
Rongbao Zhao+3 more
openaire +3 more sources
Intestinal absorption of glucose in mice as determined by positron emission tomography. [PDF]
KEY POINTS:The goal was to determine the importance of the sodium-glucose cotransporter SGLT1 and the glucose uniporter GLUT2 in intestinal glucose absorption during oral glucose tolerance tests (OGTTs) in mice.
Bindslev+37 more
core +1 more source
Architected Lattices with a Topological Transition
This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley +1 more source
Intestinal gluconeogenesis and glucose transport according to body fuel availability in rats [PDF]
Intestinal hexose absorption and gluconeogenesis have been studied in relation to refeeding after two different fasting phases: a long period of protein sparing during which energy expenditure is derived from lipid oxidation (phase II), and a later phase characterized by a rise in plasma corticosterone triggering protein catabolism (phase III).
arxiv +1 more source
Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility
Sepehr Talebian+10 more
doaj +1 more source