Results 51 to 60 of about 539,014 (352)

TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. [PDF]

PLoS ONE, 2011
Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and ...
Lauren E Kolodziej, James P Lodolce, Jonathan E Chang, Jeffrey R Schneider, Wesley A Grimm, Sarah J Bartulis, Xiaorong Zhu, Jeannette S Messer, Stephen F Murphy, Nishith Reddy, Jerrold R Turner, David L Boone   +11 more
doaj   +1 more source

Logistics and technique for combined hepatic-intestinal retrieval [PDF]

, 1992
During a 13-month period, en bloc liver-small bowel cadaveric grafts were procured for seven children and one adult. All liver grafts functioned immediately, and all but one of the recipient patients recovered.
Abu-Elmagd, K, Casavilla, A, Fung, J, Reyes, J, Selby, R, Starzl, TE, Todo, S, Tzakis, A   +7 more
core   +2 more sources

Deciphering the complex signalling systems that regulate intestinal epithelial cell death processes and shedding [PDF]

, 2017
Intestinal epithelial cells play a fundamental role in maintaining homeostasis. Shedding of intestinal cells in a controlled manner is critical to maintenance of barrier function.
Agace, Albert, Anon, Arnold, Assi, Barker, Begnaud, Boehm, Brand, Brugués, Capaldo, Chen, Cheung, Du, Dunn, Dürer, Edelblum, Eisenhoffer, Elmore, Ericsson, Farooqui, George, Gilbert, Gu, Guan, Gudipaty, Günther, Günther, Günther, Heller, Hodge, Hughes, Kaemmerer, Kiesslich, Kim, Kocgozlu, Koch, Kofoed, Kuipers, Kumar, Le, Lhocine, Lindemans, Marchiando, Melendez, Nava, Niculescu, Parker, Patnaik, Pentecost, Pentecost, Peterson, Pruteanu, Rankin, Rauch, Ravasio, Sagulenko, Sellin, Smith, Solaymani-Mohammadi, Taylor, Ubelmann, Van Itallie, VanDussen, Wang, Wang, Wang, Watson, Williams, Wong   +69 more
core   +2 more sources

AHR in the intestinal microenvironment: safeguarding barrier function

Nature Reviews Gastroenterology & Hepatology, 2021
Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that belongs to the basic helix-loop-helix (bHLH)-PAS family of transcription factors, which are evolutionarily conserved environmental sensors. In the absence of ligands, AHR resides in the cytoplasm in a complex with molecular chaperones such as HSP90, XAP2 and p23 ...
Brigitta Stockinger, Kathleen Shah, Emma Wincent   +2 more
openaire   +3 more sources

Biomarkers for monitoring intestinal health in poultry : present status and future perspectives [PDF]

, 2018
Intestinal health is determined by host (immunity, mucosal barrier), nutritional, microbial and environmental factors. Deficiencies in intestinal health are associated with shifts in the composition of the intestinal microbiome (dysbiosis), leakage of ...
Antonissen, Gunther, De Meyer, Fien, Ducatelle, Richard, Eeckhaut, Venessa, Goossens, Evy, Haesebrouck, Freddy, Van Immerseel, Filip   +6 more
core   +3 more sources

Advances in Energy Metabolism Regulation of Intestinal Stem Cell Function and the Therapeutic Advantages of Traditional Chinese Medicine [PDF]

Zhongguo quanke yixue
Intestinal stem cells are an important part of maintaining the stability of intestinal barrier function, which is closely related to intestinal homeostasis, intestinal epithelial renewal, and repair of intestinal damage.
ZHU Yan, XIAO Jin, YANG Yang, TANG Taichun, WANG Shuting, CHEN Siqi, CHEN Min
doaj   +1 more source

Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins

FEBS Open Bio, 2023
The intestinal epithelium is a single‐cell layer on the mucosal surface that absorbs food‐derived nutrients and functions as a barrier that protects mucosal integrity.
Ha‐Young Park, Jin‐Hee Yu
doaj   +1 more source

A fixed combination of probiotics and herbal extracts attenuates intestinal barrier dysfunction from inflammatory stress in an in vitro model using Caco-2 cells. [PDF]

, 2019
Background: Inflammatory Bowel Diseases (IBD), are considered a growing global disease, with about ten million people being affected worldwide. Maintenance of intestinal barrier integrity is crucial for preventing IBD onset and exacerbations. Some recent
Biagi, M, Borgonetti, V, Carnevali, I, Catanzaro, D, Cocetta, V, Giron, MC, Governa, P, Montopoli, M, Ragazzi, E   +8 more
core   +1 more source

The influence of Akkermansia muciniphila on intestinal barrier function

Gut Pathogens
Intestinal barriers play a crucial role in human physiology, both in homeostatic and pathological conditions. Disruption of the intestinal barrier is a significant factor in the pathogenesis of gastrointestinal inflammatory diseases, such as inflammatory
Chunyan Mo, Xiran Lou, Jinfang Xue, Zhuang’e Shi, Yifang Zhao, Fuping Wang, Guobing Chen   +6 more
semanticscholar   +1 more source

Intestinal barrier function in health and gastrointestinal disease [PDF]

Neurogastroenterology & Motility, 2012
AbstractDefects in intestinal barrier function are associated with diseases of the gastrointestinal (GI) tract. There is growing evidence that increases in intestinal permeability plays a pathogenic role in diseases, such as inflammatory bowel disease (IBD) and celiac disease, and functional bowel disorders, such as irritable bowel syndrome (IBS). This
M, Camilleri, K, Madsen, R, Spiller, B, Greenwood-Van Meerveld, B G, Van Meerveld, G N, Verne   +5 more
openaire   +2 more sources