Results 31 to 40 of about 297,533 (307)

AHR in the intestinal microenvironment: safeguarding barrier function

Nature Reviews Gastroenterology & Hepatology, 2021
Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that belongs to the basic helix-loop-helix (bHLH)-PAS family of transcription factors, which are evolutionarily conserved environmental sensors. In the absence of ligands, AHR resides in the cytoplasm in a complex with molecular chaperones such as HSP90, XAP2 and p23 ...
Brigitta Stockinger, Kathleen Shah, Emma Wincent   +2 more
openaire   +3 more sources

Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis [PDF]

, 2016
Important insights have recently been gained in our understanding of the intricate relationship in the intestinal milieu between the vertebrate host mucosal immune response, commensal bacteria, and helminths. Helminths are metazoan worms (macrobiota) and
Gause, William C., Maizels, Rick M.
core   +1 more source

Human Intestinal Barrier Function in Health and Disease

Clinical and Translational Gastroenterology, 2016
The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a tight barrier against the ingress of harmful substances, and protect against a reaction to omnipresent harmless compounds.
Konig, J, Wells, J, Cani, PD, Garcia-Rodenas, CL, MacDonald, T, Mercenier, A, Whyte, J, Troost, F, Brummer, R-J   +8 more
openaire   +5 more sources

Regulatory Effects of Scallop Plasmalogen on Intestinal Barrier Function and Intestinal Microbiota in High-Fat Diet-Fed Mice [PDF]

Shipin Kexue
This study investigated the effect of scallop plasmalogen (SP) on intestinal barrier function and the potential role of the gut microbiota in this effect.
CHEN Shufan, FU Xueyuan, WANG Changwei, DU Fen, LIU Chuyi, FENG Xiaomei, CAO Wanxiu, TANG Qingjuan
doaj   +1 more source

Intestinal barrier function in obesity with or without metabolic syndrome: a systematic review protocol

BMJ Open, 2021
Introduction Intestinal barrier function is dependent on the structure and function of intestinal epithelial cells and paracellular pathway. The derangement of the intestinal barrier function can originate from conditions involving local and systemic ...
Mariana Duarte Bona, Carlos Henrique de Medeiros Torres, Severina Carla Vieira Cunha Lima, Aldo Angelo Moreira Lima, Bruna Leal Lima Maciel   +4 more
doaj   +1 more source

Epidermal Growth Factor and Intestinal Barrier Function [PDF]

Mediators of Inflammation, 2016
Epidermal growth factor (EGF) is a 53-amino acid peptide that plays an important role in regulating cell growth, survival, migration, apoptosis, proliferation, and differentiation. In addition, EGF has been established to be an effective intestinal regulator helping to protect intestinal barrier integrity, which was essential for the absorption of ...
Xiaopeng Tang, Hu Liu, Shufen Yang, Zuohua Li, Jinfeng Zhong, Rejun Fang   +5 more
openaire   +3 more sources

TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. [PDF]

PLoS ONE, 2011
Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and ...
Lauren E Kolodziej, James P Lodolce, Jonathan E Chang, Jeffrey R Schneider, Wesley A Grimm, Sarah J Bartulis, Xiaorong Zhu, Jeannette S Messer, Stephen F Murphy, Nishith Reddy, Jerrold R Turner, David L Boone   +11 more
doaj   +1 more source

Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations [PDF]

, 2019
The contribution of the intestinal tract to differences in residual feed intake (RFI) has been inconclusively studied in chickens so far. It is also not clear if RFI-related differences in intestinal function are similar in chickens raised in different ...
Aschenbach, J., Ball, M. E. E., Ertl, R., Hawken, R. J., Hollmann, M., Lawlor, P. G. [u.v.m.], Magowan, E., Metzler-Zebeli, B. U., Molnár, A., Witter, K.   +9 more
core   +1 more source

Artificial Nutrition and Intestinal Mucosal Barrier Functionality [PDF]

Digestion, 2013
The gastrointestinal tract has a major role in digestion and absorption of nutrients while playing a leading role in defense of the body. It forms a shield against the invasion of various microorganisms or their products (e.g. antigens, toxins) and therefore it is important to establish its integrity and functionality.
Chrysostomos D, Anastasilakis, Orestis, Ioannidis, Athina I, Gkiomisi, Dimitrios, Botsios   +3 more
openaire   +2 more sources

Advances in Energy Metabolism Regulation of Intestinal Stem Cell Function and the Therapeutic Advantages of Traditional Chinese Medicine [PDF]

Zhongguo quanke yixue
Intestinal stem cells are an important part of maintaining the stability of intestinal barrier function, which is closely related to intestinal homeostasis, intestinal epithelial renewal, and repair of intestinal damage.
ZHU Yan, XIAO Jin, YANG Yang, TANG Taichun, WANG Shuting, CHEN Siqi, CHEN Min
doaj   +1 more source