Results 11 to 20 of about 297,533 (307)

Intestinal Barrier Function in Gluten-Related Disorders [PDF]

Nutrients, 2019
Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Schumann, Michael, Withoff, Sebo   +6 more
core   +5 more sources

Adenosine in Intestinal Epithelial Barrier Function

Cells
At the intestinal front, several lines of defense are in place to resist infection and injury, the mucus layer, gut microbiome and strong epithelial junctions, to name a few. Their collaboration creates a resilient barrier.
Mariya Stepanova, Carol M. Aherne
doaj   +3 more sources

Regulation of Intestinal Barrier Function by Microbial Metabolites [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2021
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that continually shapes host pathophysiological responses. Despite readily available abundant metagenomic data, the functional dynamics of gut microbiota remain to be explored in various health and disease conditions.
Sweta Ghosh, Caleb Samuel Whitley, Bodduluri Haribabu, Venkatakrishna Rao Jala   +3 more
openaire   +3 more sources

Helminths and intestinal barrier function [PDF]

Tissue Barriers, 2017
Approximately one-sixth of the worlds' population is infected with helminths and this class of parasite takes a major toll on domestic livestock. The majority of species of parasitic helminth that infect mammals live in the gut (the only niche for tapeworms) where they contact the hosts' epithelial cells.
Derek M, McKay, Adam, Shute, Fernando, Lopes   +2 more
openaire   +2 more sources

Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis

Newborn, 2022
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal barrier is altered in NEC, which potentially contributes to its pathogenesis by promoting intestinal bacterial translocation and stimulating the inflammatory response.
Managlia, Elizabeth, Yan, Xiaocai, De Plaen, Isabelle G   +2 more
openaire   +2 more sources

Review article: Intestinal epithelia and barrier functions [PDF]

Alimentary Pharmacology & Therapeutics, 1997
SUMMARYThe mucosal epithelia of the digestive tract acts as a selective barrier, permeable to ions, small molecules and macromolecules. These epithelial cells aid the digestion of food and absorption of nutrients. They contribute to the protection against pathogens and undergo continuous cell renewal which facilitates the elimination of damaged cells ...
J P, Kraehenbuhl, E, Pringault, M R, Neutra   +2 more
openaire   +2 more sources

Impact of dietary manganese on intestinal barrier and inflammatory response in broilers challenged with Salmonella Typhimurium [PDF]

, 2020
Growing concern for public health and food safety has prompted a special interest in developing nutritional strategies for removing waterborne and foodborne pathogens, including Salmonella.
Bai, Jie, Bai, Shiping, Ding, Xuemei, Michiels, Joris, Pan, Shuqin, Peng, Huanwei, Su, Zhuowei, Wang, Jianping, Xuan, Yue, Zeng, Qiufeng, Zhang, Huaiyong, Zhang, Keying   +11 more
core   +2 more sources

Intestinal barrier functions in hematologic and oncologic diseases

Journal of Translational Medicine, 2023
AbstractThe intestinal barrier is a complex structure that not only regulates the influx of luminal contents into the systemic circulation but is also involved in immune, microbial, and metabolic homeostasis. Evidence implicating disruption in intestinal barrier functions in the development of many systemic diseases, ranging from non-alcoholic ...
Elio Haroun, Prashanth Ashok Kumar, Ludovic Saba, Joseph Kassab, Krishna Ghimire, Dibyendu Dutta, Seah H. Lim   +6 more
openaire   +3 more sources

P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency

Frontiers in Cell and Developmental Biology, 2021
This study aimed to determine whether Bmi-1 deficiency leads to intestinal epithelial barrier destruction and microbiota dysfunction, which members of the microbial community alter barrier function with age, and whether p16INK4a deletion could reverse ...
Jiawen Zhou, Chenxing Hou, Haiyun Chen, Ziyue Qin, Zi’an Miao, Jingyu Zhao, Qiuyi Wang, Min Cui, Chunfeng Xie, Rong Wang, Qing Li, Guoping Zuo, Dengshun Miao, Dengshun Miao, Jianliang Jin   +14 more
doaj   +1 more source

The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]

, 2009
The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Bracarense, Ana-Paula, Del Rio, Juan-Carlos, Ferrier, Laurent, Kolf-Clauw, Martine, Marin, Daniela E., Moreno, Carolina, Nougayrède, Jean-Philippe, Oswald, Isabelle P, Pinton, Philippe   +8 more
core   +2 more sources