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Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases [PDF]

open access: yesFrontiers in Microbiology, 2018
The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota contributes to balancing the immune system to maintain host ...
Maria C. Opazo   +11 more
openaire   +9 more sources

Identification of Vitamin D-related gene signature to predict colorectal cancer prognosis [PDF]

open access: yesPeerJ, 2021
Colorectal cancer (CRC) is one of the most common malignant carcinomas worldwide with poor prognosis, imposing an increasingly heavy burden on patients.
Luping Bu   +8 more
doaj   +2 more sources

Meckel’s Diverticulum Diagnosed by Balloon-Assisted Enteroscopy: A Multicenter Report from the Taiwan Association for the Study of Small Intestinal Diseases (TASSID)

open access: yesGastroenterology Research and Practice, 2021
Background and Aims. Patients with Meckel’s diverticulum (MD) are difficult to preoperatively diagnose because of its endoscopic inaccessibility. Balloon-assisted enteroscopy (BAE) allows endoscopic access to the entire small intestine.
Jen-Wei Chou   +16 more
doaj   +1 more source

Integrated analysis of the gut microbiome and metabolome in a mouse model of inflammation-induced colorectal tumors

open access: yesFrontiers in Microbiology, 2023
Colorectal cancer (CRC) is a common malignancy worldwide, and the gut microbiota and metabolites play an important role in its initiation and progression.
Yuntian Hong   +15 more
doaj   +1 more source

Long-Term Administration of Anthraquinone Rhein on Induction of Constipation in Sprague-Dawley Rats via SCF/c-Kit Signaling Pathways

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2021
Background and Study Aims. It has been shown that abuse of laxatives is becoming a serious problem; therefore, a comprehensive understanding of its effect and possible mechanism on colon motility is essential to select effective treatments and avoid ...
Bo Zhang   +5 more
doaj   +1 more source

Pathogenesis and therapy of radiation enteritis with gut microbiota

open access: yesFrontiers in Pharmacology, 2023
Radiotherapy is widely used in clinic due to its good effect for cancer treatment. But radiotherapy of malignant tumors in the abdomen and pelvis is easy to cause radiation enteritis complications.
Qilin Yang   +6 more
doaj   +1 more source

Identification of Pharmacological Autophagy Regulators of Active Ulcerative Colitis

open access: yesFrontiers in Pharmacology, 2021
Background: Ulcerative colitis (UC) is a chronic recurrent disease of unknown etiology. Recently, it has been reported that autophagy-related gene polymorphism is closely associated with increased risk of UC, and the therapeutic effect of some UC drugs ...
Peishan Qiu   +19 more
doaj   +1 more source

Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Ferroptosis, a type of cell death triggered by excessive accumulation of iron-dependent lipid peroxidation, possesses an excellent potential in cancer treatment.
Qian Hu   +20 more
doaj   +1 more source

Predicting Distant Metastasis in Young-Onset Colorectal Cancer After Surgery: A Retrospective Study

open access: yesFrontiers in Oncology, 2022
BackgroundAlthough overall colorectal cancer (CRC) cases have been declining worldwide, there has been an increase in the incidence of the CRC among individuals younger than 50 years old, which is associated with distant metastasis (DM) and poor ...
Jie Cheng   +17 more
doaj   +1 more source

Histopathology of the gut in rheumatic diseases [PDF]

open access: yes, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F.   +4 more
core   +1 more source

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