Results 21 to 30 of about 9,797,826 (264)

Integrated analysis of the gut microbiome and metabolome in a mouse model of inflammation-induced colorectal tumors

Frontiers in Microbiology, 2023
Colorectal cancer (CRC) is a common malignancy worldwide, and the gut microbiota and metabolites play an important role in its initiation and progression.
Yuntian Hong, Yuntian Hong, Yuntian Hong, Baoxiang Chen, Baoxiang Chen, Baoxiang Chen, Xiang Zhai, Xiang Zhai, Xiang Zhai, Qun Qian, Qun Qian, Qun Qian, Rui Gui, Congqing Jiang, Congqing Jiang, Congqing Jiang   +15 more
doaj   +1 more source

Tuft Cells and Their Role in Intestinal Diseases

Frontiers in Immunology, 2022
The interests in intestinal epithelial tuft cells, their basic physiology, involvement in immune responses and relevance for gut diseases, have increased dramatically over the last fifteen years.
Sebastian Kjærgaard Hendel, L. Kellermann, Annika Hausmann, N. Bindslev, K. Jensen, O. Nielsen   +5 more
semanticscholar   +1 more source

Native and Engineered Probiotics: Promising Agents against Related Systemic and Intestinal Diseases

International Journal of Molecular Sciences, 2022
Intestinal homeostasis is a dynamic balance involving the interaction between the host intestinal mucosa, immune barrier, intestinal microecology, nutrients, and metabolites.
Haokun Shen, Zitong Zhao, Zengjue Zhao, Yuyi Chen, Linghua Zhang   +4 more
semanticscholar   +1 more source

Pathogenesis and therapy of radiation enteritis with gut microbiota

Frontiers in Pharmacology, 2023
Radiotherapy is widely used in clinic due to its good effect for cancer treatment. But radiotherapy of malignant tumors in the abdomen and pelvis is easy to cause radiation enteritis complications.
Qilin Yang, Qilin Yang, Bingzhi Qin, Weiliang Hou, Weiliang Hou, Huanlong Qin, Fang Yin   +6 more
doaj   +1 more source

Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases

Frontiers in Microbiology, 2022
The fucosyltransferase 2 gene (FUT2) mediates the synthesis of histoblood group antigens (HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal epithelial cells and body fluids.
Mingyang Hu, Xiyun Zhang, Jinze Li, Luotong Chen, Xiaolin He, Tingting Sui   +5 more
semanticscholar   +1 more source

Long-Term Administration of Anthraquinone Rhein on Induction of Constipation in Sprague-Dawley Rats via SCF/c-Kit Signaling Pathways

Canadian Journal of Gastroenterology and Hepatology, 2021
Background and Study Aims. It has been shown that abuse of laxatives is becoming a serious problem; therefore, a comprehensive understanding of its effect and possible mechanism on colon motility is essential to select effective treatments and avoid ...
Bo Zhang, Mingdong Huo, Zhicheng Chen, Feng Gao, Yan Liu, Xingxin Zhou   +5 more
doaj   +1 more source

Oral Microbiota and Salivary Levels of Oral Pathogens in Gastro-Intestinal Diseases: Current Knowledge and Exploratory Study

Microorganisms, 2021
Various bi-directional associations exist between oral health and gastro-intestinal diseases. The oral microbiome plays a role in the gastro-intestinal carcinogenesis and fusobacteria are the most investigated bacteria involved. This paper aims to review
M. Contaldo, A. Fusco, P. Stiuso, S. Lama, A. Gravina, A. Itro, A. Federico, A. Itro, G. Dipalma, F. Inchingolo, R. Serpico, G. Donnarumma   +11 more
semanticscholar   +1 more source

Trace Element Selenium Effectively Alleviates Intestinal Diseases

International Journal of Molecular Sciences, 2021
Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the form of selenoproteins and has a variety of biological functions.
Ruihua Ye, Jiaqiang Huang, Zixu Wang, Yaoxing Chen, Yulan Dong   +4 more
semanticscholar   +1 more source

Identification of Pharmacological Autophagy Regulators of Active Ulcerative Colitis

Frontiers in Pharmacology, 2021
Background: Ulcerative colitis (UC) is a chronic recurrent disease of unknown etiology. Recently, it has been reported that autophagy-related gene polymorphism is closely associated with increased risk of UC, and the therapeutic effect of some UC drugs ...
Peishan Qiu, Peishan Qiu, Lan Liu, Lan Liu, Jun Fang, Jun Fang, Meng Zhang, Meng Zhang, Haizhou Wang, Haizhou Wang, Yanan Peng, Yanan Peng, Min Chen, Min Chen, Jing Liu, Jing Liu, Fan Wang, Fan Wang, Qiu Zhao, Qiu Zhao   +19 more
doaj   +1 more source

Biological characteristics of IL-6 and related intestinal diseases

International Journal on Biological Sciences, 2021
The intestine serves as an important digestive and the largest immune organ in the body. Interleukin-6(IL-6), an important mediator of various pathways, participates in the interactions between different kinds of cells and closely correlates with ...
Yuexin Guo, Bo-ya Wang, Tiantian Wang, Lei Gao, Ze-Jun Yang, Fei-fei Wang, H. Shang, Rongxuan Hua, Jing-dong Xu   +8 more
semanticscholar   +1 more source