MiR-21-3p Promotes Hepatocellular Carcinoma Progression via SMAD7/YAP1 Regulation
BackgroundHepatocellular carcinoma (HCC) remains a major global health burden due to its high prevalence and mortality. Emerging evidence reveals that microRNA (miRNA) plays a vital role in cancer pathogenesis and is widely involved in the regulation of ...
Yinghui Hong+21 more
doaj +1 more source
Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip [PDF]
The intestinal epithelium is a critical component of the gut barrier. Composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure prevents the transfer of harmful microorganisms, antigens ...
A. J. M. Watson+15 more
core +3 more sources
Immunoglobulin A and liver diseases. [PDF]
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core +2 more sources
Role of Smooth Muscle in Intestinal Inflammation
The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD).
Stephen M Collins+4 more
doaj +1 more source
Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis [PDF]
The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the ...
Banu, Petrisor+3 more
core +3 more sources
Gut Metagenome as a Potential Diagnostic and Predictive Biomarker in Slow Transit Constipation
Slow transit constipation (STC) is one of the most frequent gastrointestinal diagnoses. In this study, we conducted a quantitative metagenomics study in 118 Chinese individuals.
Hongliang Tian+23 more
doaj +1 more source
Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E.+3 more
core +1 more source
DISEASES OF THE STOMACH AND INTESTINES [PDF]
Includes index. ; Publisher's catalog comprises last 16 pages. ; Mode of access: Internet.
openaire +3 more sources
Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer : diagnostic and therapeutic potential [PDF]
Caspases are a group of proteolytic enzymes involved in the co-ordination of cellular processes, including cellular homeostasis, inflammation and apoptosis.
Caiazza, F+12 more
core +2 more sources
Eosinophilic Intestinal Disease [PDF]
n ...
openaire +2 more sources