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Intestinal epithelial replacement by transplantation of cultured murine and human cells into the small intestine. [PDF]

open access: yesPLoS ONE, 2019
Adult intestinal epithelial stem cells are a promising resource for treatment of intestinal epithelial disorders that cause intestinal failure and for intestinal tissue engineering.
Hassan A Khalil   +9 more
doaj   +3 more sources

Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-α-induced apoptosis in the intestinal epithelium. [PDF]

open access: yesPLoS Biology, 2012
Intestinal epithelial cells exist within a complex environment that affects how they interpret and respond to stimuli. We have applied a multi-scale in vivo systems approach to understand how intestinal immune cells communicate with epithelial cells to ...
Ken S Lau   +5 more
doaj   +6 more sources

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models [PDF]

open access: yesAdvanced Science
Hepatic progenitor cells (HPCs) are frequently overactivated, and their differentiation into hepatocytes is impaired in advanced liver diseases. To explore the effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of ...
Liang Ye   +16 more
doaj   +2 more sources

Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. [PDF]

open access: yes, 2016
Background & aimsIntestinal microfold (M) cells are specialized epithelial cells that act as gatekeepers of luminal antigens in the intestinal tract.
Dunn, James CY   +11 more
core   +10 more sources

Infection of porcine enteroids and 2D differentiated intestinal epithelial cells with rotavirus A to study cell tropism and polarized immune response

open access: yesEmerging Microbes and Infections, 2023
Intestinal epithelial cell interactions with enteric pathogens have been incompletely elucidated owing to the lack of model systems that recapitulate the cellular diversity, architecture and functionality of the intestine.
Miaomiao Yan   +8 more
doaj   +1 more source

Intestinal epithelial cells necroptosis and its association with intestinal inflammation [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy, 2019
This review focuses on the role of necroptosis, an alternative mode of cell death, in the pathogenesis of diseases associated with intestinal inflammation whose prevalence has been significantly increased for last decades, which substantiates the ...
Anton S. Tkachenko
doaj   +1 more source

MiR-221/222 Ameliorates Deoxynivalenol-Induced Apoptosis and Proliferation Inhibition in Intestinal Epithelial Cells by Targeting PTEN

open access: yesFrontiers in Cell and Developmental Biology, 2021
Intestinal epithelial cells are critical for nutrient absorption and defending against pathogen infection. Deoxynivalenol (Don), the most common mycotoxin, contaminates cereals and food throughout the world, causes serious damage to mammal intestinal ...
Lianjie Hou   +5 more
doaj   +1 more source

Alpha-Lipoic Acid Promotes Intestinal Epithelial Injury Repair by Regulating MAPK Signaling Pathways

open access: yesMediators of Inflammation, 2022
Intestinal epithelial cells are an essential barrier in human gastrointestinal tract, and healing of epithelial wound is a key process in many intestinal diseases.
Yu Yang   +6 more
doaj   +1 more source

The Glucocorticoid Receptor in Intestinal Epithelial Cells Alleviates Colitis and Associated Colorectal Cancer in MiceSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Inflammatory bowel disease is commonly treated by administration of glucocorticoids. While the importance of intestinal epithelial cells for the pathogenesis of this disorder is widely accepted, their role as target cells for ...
Chiara Muzzi   +6 more
doaj   +1 more source

Intestinal epithelial BLT1 promotes mucosal repair

open access: yesJCI Insight, 2022
Acute and chronic intestinal inflammation is associated with epithelial damage, resulting in mucosal wounds in the forms of erosions and ulcers in the intestinal tract.
Shusaku Hayashi   +7 more
doaj   +1 more source

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