Results 11 to 20 of about 263,980 (286)

Intestinal epithelium in inflammatory bowel disease [PDF]

Frontiers in Medicine, 2014
The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs)
Mehmet eCoskun
doaj   +3 more sources

Hyperproliferation of the Intestinal Epithelium [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2021
Christopher M. Dekaney, PhD
doaj   +2 more sources

Barrett’s Esophagus and Intestinal Metaplasia

Frontiers in Oncology, 2021
Intestinal metaplasia refers to the replacement of the differentiated and mature normal mucosal epithelium outside the intestinal tract by the intestinal epithelium.
Lu Zhang, Binyu Sun, Xi Zhou, QiongQiong Wei, Sicheng Liang, Gang Luo, Tao Li, Muhan Lü   +7 more
doaj   +1 more source

Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake

Journal of Lipid Research, 2008
The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to overexpress I-FABP and compared with cells treated with
Alain Montoudis, Ernest Seidman, François Boudreau, Jean-François Beaulieu, Daniel Menard, Mounib Elchebly, Geneviève Mailhot, Alain-Theophile Sane, Marie Lambert, Edgard Delvin, Emile Levy   +10 more
doaj   +1 more source

Fast drosophila enterocyte regrowth after infection involves a reverse metabolic flux driven by an amino acid transporter

iScience, 2023
Summary: Upon exposure to a bacterial pore-forming toxin, enterocytes rapidly purge their apical cytoplasm into the gut lumen, resulting in a thin intestinal epithelium.
Catherine Socha, Inês S. Pais, Kwang-Zin Lee, Jiyong Liu, Samuel Liégeois, Matthieu Lestradet, Dominique Ferrandon   +6 more
doaj   +1 more source

Mend Your FencesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
The intestinal epithelium can be easily disrupted during gut inflammation as seen in inflammatory bowel disease (IBD), such as ulcerative colitis or Crohn’s disease.
Eva Martini, Susanne M. Krug, Britta Siegmund, Markus F. Neurath, Christoph Becker   +4 more
doaj   +1 more source

PLK1 protects intestinal barrier function during sepsis by targeting mitochondrial dynamics through TANK-NF-κB signalling

Molecular Medicine, 2022
Background Intestinal barrier integrity in the pathogenesis of sepsis is critical. Despite an abundance of evidence, the molecular mechanism of the intestinal barrier in sepsis pathology remains unclear.
Ying-Ya Cao, Yuan Zhang, Wuyun Gerile, Yan Guo, Li-Na Wu, Li-Li Wu, Kai Song, Wei-Hua Lu, Jian-Bo Yu   +8 more
doaj   +1 more source

The Production and Function of Endogenous Interleukin-10 in Intestinal Epithelial Cells and Gut HomeostasisSummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
The healthy gut is achieved and maintained through a balanced relationship between the mucosal immune system, microbial communities resident in the lumen, and the intestinal epithelium.
Huong D. Nguyen, Hanan M. Aljamaei, Andrew W. Stadnyk   +2 more
doaj   +1 more source

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. [PDF]

, 2018
Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking.
Bayrer, James R, Escusa, Hazel S, Fletterick, Robert J, Ingraham, Holly A, Klein, Ophir D, Moore, David D, Nattiv, Roy, Suzawa, Miyuki, Wang, Hongtao   +8 more
core   +2 more sources

Surface Structure of Intestinal Epithelium

Gastroenterology, 1970
Summary Specimens of human and rat small intestine were studied by scanning electron microscopy. Human specimens were examined intact, while rat specimens were studied after partial or complete dissociation of epithelium from the underlying villus core. The present technique confirms, in a simple, direct way, previous concepts of the three-dimensional
S P, Balcerzak, W C, Lane, J W, Bullard
openaire   +2 more sources