The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]
, 2009 The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Bracarense, Ana-Paula +8 more
core +2 more sources
The Role of Lactoferrin in Intestinal Health
Pharmaceutics, 2023 The intestine represents one of the first barriers where microorganisms and environmental antigens come into tight contact with the host immune system. A healthy intestine is essential for the well-being of humans and animals. The period after birth is a very important phase of development, as the infant moves from a protected environment in the uterus
Celia Conesa +3 more
openaire +5 more sources
Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea [PDF]
, 2018 Background: Environmental enteric dysfunction (EED) is widespread throughout the tropics and in children is associated with stunting and other adverse health outcomes. One of the hallmarks of EED is villus damage.
Amadi, B +9 more
core +9 more sources
Primary Cilium Identifies a Quiescent Cell Population in the Human Intestinal Crypt
Cells, 2023 Primary cilia are sensory antennae located at the cell surface which mediate a variety of extracellular signals involved in development, tissue homeostasis, stem cells and cancer.
Blanche Sénicourt +6 more
doaj +1 more source
Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; Conversion of isoxanthohumol into 8-prenylnaringenin [PDF]
, 2005 Hop, an essential ingredient in most beers, contains a number of prenylflavonoids, among which 8-prenylnaringenin (8-PN) would be the most potent phytoestrogen currently known. Although a number of health effects are attributed to these compounds, only a
De Keukeleire, Denis +4 more
core +2 more sources
Separation of Oligosaccharides from Lotus Seeds via Medium-pressure Liquid Chromatography Coupled with ELSD and DAD [PDF]
, 2017 peer-reviewedLotus seeds were identified by the Ministry of Public Health of China as both food and medicine. One general function of lotus seeds is to improve intestinal health.
AD Orozco-Cortes +39 more
core +1 more source
Optimization, Characteristics, and Functions of Alkaline Phosphatase From Escherichia coli
Frontiers in Microbiology, 2022 Weaning of piglets could increase the risk of infecting with Gram-negative pathogens, which can further bring about a wide array of virulence factors including the endotoxin lipopolysaccharide (LPS).
Yachao Dong +19 more
doaj +1 more source
Intestinal Microbiota and Health in Childhood
Bioscience and Microflora, 2011 Western medicine has only recently discovered that the intestinal microbiota is a major determinant of the well-being of the host. Although it would be oversimplifying to limit the benefits of breastfeeding compared to cow milk based infant formula to differences in gastrointestinal flora, the impact of the latter has been demonstrated beyond doubt. As
Vandenplas, Yvan +5 more
openaire +4 more sources
Role of Vitamin K in Intestinal Health [PDF]
Frontiers in Immunology, 2022 Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer (CRC) generally characterized by clinical symptoms, including malabsorption, intestinal dysfunction, injury, and microbiome imbalance, as well as certain secondary intestinal disease complications, continue to be serious public health problems worldwide.
Yujiao Lai +4 more
openaire +3 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Unsuccessful clinical translation of orally delivered biological drugs remains a challenge in pharmaceutical development and has been linked to insufficient mechanistic understanding of intestinal drug transport.
Arjen Weller +18 more
doaj +1 more source