Results 1 to 10 of about 190,131 (263)
NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
Frontiers in Immunology, 2022 Intestinal immunity and homeostasis are maintained through the regulation of cytokine trafficking, microbiota, necrosis and apoptosis. Intestinal immunity and homeostasis participate in host defenses and inflammatory responses locally or systemically ...
Bingran Wang +3 more
doaj +3 more sources
Vitamin-mediated regulation of intestinal immunity [PDF]
Frontiers in Immunology, 2013 The intestine is exposed continuously to complex environments created by numerous injurious and beneficial non-self antigens. The unique mucosal immune system in the intestine maintains the immunologic homeostasis between the host and the external ...
Jun eKunisawa +3 more
doaj +3 more sources
Stem Cell Research, 2023 Mutations in UNC45A, a co-chaperone for myosins, were recently found causative of a syndrome combining cholestasis, diarrhea, loss of hearing and bone fragility.
Celine Banal +7 more
doaj +1 more source
Intestinal intraepithelial lymphocytes: Maintainers of intestinal immune tolerance and regulators of intestinal immunity [PDF]
Journal of Leukocyte Biology, 2020 Abstract Intestinal immune tolerance is essential for the immune system, as it prevents abnormal immune responses to large quantities of antigens from the intestinal lumen, such as antigens from commensal microorganisms, and avoids self-injury.
Ma, Haitao, Qiu, Yuan, Yang, Hua
openaire +2 more sources
Iron and intestinal immunity [PDF]
Current Opinion in Gastroenterology, 2011 Recent advances in the study of iron metabolism have led to a better understanding of the molecular basis for the interactions between iron and the inflammatory response. We will review this new information in the context of the gastrointestinal tract.The effects of iron on microbial enteropathogens are well known.
Bobby J, Cherayil +2 more
openaire +2 more sources
Intestinal immunity: to be, or not to be, induced? That is the question [PDF]
International Immunology, 2021 Abstract The intestinal immune system maintains intestinal homeostasis in collaboration with diverse immune cell subsets residing at the epithelial layer, lamina propria and gut-associated lymphoid tissue (GALT). Bacterial components and their metabolites are essential for the establishment of the gut immune system.
Daisuke Takahashi +2 more
openaire +2 more sources
The impact of aging on intestinal mucosal immune function and clinical applications
Frontiers in Immunology, 2022 Immune cells and immune molecules in the intestinal mucosa participate in innate and adaptive immunity to maintain local and systematic homeostasis. With aging, intestinal mucosal immune dysfunction will promote the emergence of age-associated diseases ...
Han Zheng +5 more
doaj +1 more source
Intestinal fungi and antifungal secretory immunoglobulin A in Crohn’s disease
Frontiers in Immunology, 2023 The human gastrointestinal tract harbors trillions of commensal microorganisms. Emerging evidence points to a possible link between intestinal fungal dysbiosis and antifungal mucosal immunity in inflammatory bowel disease, especially in Crohn’s disease ...
Meng Sun +3 more
doaj +1 more source
Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation
Cell & Bioscience, 2023 Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that has significant immunotoxic effects.
Yue Chen +4 more
doaj +1 more source
The Intestinal Virome and Immunity [PDF]
The Journal of Immunology, 2018 Abstract The composition of the human microbiome is considered a major source of interindividual variation in immunity and, by extension, susceptibility to diseases. Intestinal bacteria have been the major focus of research.
Jessica A Neil, Ken Cadwell
openaire +2 more sources