Results 21 to 30 of about 190,131 (263)

Molecular Control of Innate Immune Response to Pseudomonas aeruginosa Infection by Intestinal let-7 in Caenorhabditis elegans. [PDF]

PLoS Pathogens, 2017
The microRNA (miRNA) let-7 is an important miRNA identified in Caenorhabditis elegans and has been shown to be involved in the control of innate immunity. The underlying molecular mechanisms for let-7 regulation of innate immunity remain largely unclear.
Lingtong Zhi, Yonglin Yu, Xueying Li, Daoyong Wang, Dayong Wang   +4 more
doaj   +1 more source

The Effects of a High-Fat Diet on Inflammatory Bowel Disease

Biomolecules, 2023
The interactions among diet, intestinal immunity, and microbiota are complex and play contradictory roles in inflammatory bowel disease (IBD). An increasing number of studies has shed light on this field.
Yuan Dang, Chunxiang Ma, Kexin Chen, Yiding Chen, Mingshan Jiang, Kehan Hu, Lili Li, Zhen Zeng, Hu Zhang   +8 more
doaj   +1 more source

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity

Cell Reports, 2022
Summary: Systemic immunity is stringently regulated by commensal intestinal microbes, including the pathobiont Candida albicans. This fungus utilizes various transcriptional and morphological programs for host adaptation, but how this heterogeneity ...
Tzu-Yu Shao, Pallavi Kakade, Jessica N. Witchley, Corey Frazer, Kathryn L. Murray, Iuliana V. Ene, David B. Haslam, Thomas Hagan, Suzanne M. Noble, Richard J. Bennett, Sing Sing Way   +10 more
doaj   +1 more source

Innate immunity in the small intestine [PDF]

Current Opinion in Gastroenterology, 2011
In this article, we provide an update of the latest findings related to the innate immunity in the small intestine. In particular, we will focus on innate immune receptors and antimicrobial strategies that keep luminal bacteria and viral pathogens under control to avoid mucosal damage.
Rebeca, Santaolalla, Masayuki, Fukata, Maria T, Abreu   +2 more
openaire   +2 more sources

Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement

Cell Death Discovery, 2023
Hepatocellular carcinoma (HCC), the most prevalent type of aggressive liver cancer, accounts for the majority of liver cancer diagnoses and fatalities. Despite recent advancements in HCC treatment, it remains one of the deadliest cancers.
Huijie Jia, Pengkun Wei, Shijie Zhou, Yuanyuan Hu, Chunjing Zhang, Lirui Liang, Bingqing Li, Zerui Gan, Yuanling Xia, Hanyu Jiang, Mingguang Shao, Sheng Guo, Zishan Yang, Jiateng Zhong, Feng Ren, Huiyong Zhang, Yongxi Zhang, Tiesuo Zhao   +17 more
doaj   +1 more source

Immunomodulatory effects of inulin and its intestinal metabolites

Frontiers in Immunology, 2023
“Dietary fiber” (DF) refers to a type of carbohydrate that cannot be digested fully. DF is not an essential nutrient, but it plays an important part in enhancing digestive capacity and maintaining intestinal health.
Wei Sheng, Guang Ji, Li Zhang
doaj   +1 more source

The role of CD103+ Dendritic cells in the intestinal mucosal immune system.

Frontiers in Immunology, 2011
While dendritic cells (DC) are central to the induction and regulation of adaptive immunity, these cells are very heterogenous and specific subsets can be characterized based on the expression of cell surface markers and functional properties. Intestinal
Darren Thomas Ruane, Ed Charles Lavelle
doaj   +1 more source

Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers

Journal of Animal Science and Biotechnology, 2023
Background The interaction between nutrition and immunity plays a vital role in nutrient digestion, absorption, and metabolism during poultry production.
Xinkai Wang, Yifan Hu, Xiaoyan Zhu, Liyuan Cai, Muhammad Zahid Farooq, Xianghua Yan   +5 more
doaj   +1 more source

Effects of Lactococcus lactis on the Intestinal Functions in Weaning Piglets

Frontiers in Nutrition, 2021
Post-weaning diarrhea of piglets is associated with gut microbiota dysbiosis and intestinal pathogen infection. Recent studies have shown that Lactococcus lactis (L.lactis) could help suppress pathogen infection.
Dongming Yu, Dongming Yu, Yaoyao Xia, Liangpeng Ge, Bie Tan, Bie Tan, Bie Tan, Bie Tan, Shuai Chen, Shuai Chen, Shuai Chen, Shuai Chen   +11 more
doaj   +1 more source

Innate immunity in the small intestine [PDF]

Current Opinion in Gastroenterology, 2012
This article reviews the most recent publications on innate immunity in the small intestine. We will go over the innate immune receptors that act as sensors of microbial presence or cell injury, Paneth cells as the main epithelial cell type that secrete antimicrobial peptides, and mucosal production of immunoglobulin A (IgA).
Rebeca, Santaolalla, Maria T, Abreu
openaire   +2 more sources