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High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. [PDF]
PLoS ONE, 2015 The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue,
Andrew M F Johnson +6 more
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Intestinal Permeability: The Basics [PDF]
Canadian Journal of Gastroenterology, 1995 The authors review some of the more fundamental principles underlying the noninvasive assessment of intestinal permeability in humans, the choice of test markers and their analyses, and the practical aspects of test dose composition and how these can be ...
Ingvar Bjarnason +2 more
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Intestinal permeability in strongyloidiasis [PDF]
Brazilian Journal of Medical and Biological Research, 2001 The objective of the present study was to assess intestinal permeability in patients with infection caused by Strongyloides stercoralis. Twenty-six patients (16 women and 10 men), mean age 45.9, with a diagnosis of strongyloidiasis were evaluated.
A.L. Werneck-Silva +5 more
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Intestinal Ketogenesis and Permeability [PDF]
International Journal of Molecular SciencesConsumption of a high-fat diet (HFD) has been suggested as a contributing factor behind increased intestinal permeability in obesity, leading to increased plasma levels of microbial endotoxins and, thereby, increased systemic inflammation. We and others have shown that HFD can induce jejunal expression of the ketogenic rate-limiting enzyme ...
Anna Casselbrant +6 more
openaire +4 more sources
Intestinal permeability of N-acetylcysteine is driven by gut microbiota-dependent cysteine palmitoylation [PDF]
Nature CommunicationsTrillions of intestinal microbiota are essential to the permeability of orally administered drugs. However, identifying microbial-drug interactions remains challenging due to the highly variable composition of intestinal flora among individuals.
Yu-Hang Zhang +7 more
doaj +2 more sources
Gut cannabinoid receptor 1 regulates alcohol binge-induced intestinal permeability [PDF]
eGastroenterologyBackground Endocannabinoids acting via cannabinoid receptor 1 (CB1R) can elicit increased intestinal permeability (a condition also called ‘leaky gut’).
Bin Gao +6 more
doaj +2 more sources
Intestinal Permeability Assays: a Review
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2021 Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality ...
A. A. Iakupova +4 more
doaj +1 more source
iScience, 2023 Summary: Studies have reported increased intestinal permeability in multiple sclerosis (MS) patients and its mouse model experimental autoimmune encephalomyelitis (EAE).
Paola Bianchimano +11 more
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Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy
Cells, 2022 Protease-activated receptor 2 (PAR2) alleviates intestinal inflammation by upregulating autophagy. PAR2 also modulates tight junctions through β-arrestin signaling.
Yuju Kim +7 more
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Psychosocial stress-induced intestinal permeability in healthy humans: What is the evidence?
Neurobiology of Stress, 2023 An impaired intestinal barrier function can be detrimental to the host as it may allow the translocation of luminal antigens and toxins into the subepithelial tissue and bloodstream. In turn, this may cause local and systemic immune responses and lead to
Danique La Torre +3 more
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