Results 31 to 40 of about 234,915 (329)

Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]

, 2020
Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz, Hauser, Anja E., Kröger, Susan, Martínez-Vallespín, Beatriz, Niesner, Raluca, Pieper, Robert, Vahjen, Wilfried, Zentek, Jürgen   +7 more
core   +1 more source

Intestinal permeability. [PDF]

Gut, 1994
Damage to the mucosal barrier may be assessed, non-invasively by use of sugar probes, which permeate through the transcellular or paracellular (tight junction) routes. A standardised test, with analysis of a five hour urine collection has proved useful in studying the sequelae of non-steroid anti-inflammatory drug (NSAID) administration, untreated ...
openaire   +2 more sources

A fixed combination of probiotics and herbal extracts attenuates intestinal barrier dysfunction from inflammatory stress in an in vitro model using Caco-2 cells. [PDF]

, 2019
Background: Inflammatory Bowel Diseases (IBD), are considered a growing global disease, with about ten million people being affected worldwide. Maintenance of intestinal barrier integrity is crucial for preventing IBD onset and exacerbations. Some recent
Biagi, M, Borgonetti, V, Carnevali, I, Catanzaro, D, Cocetta, V, Giron, MC, Governa, P, Montopoli, M, Ragazzi, E   +8 more
core   +1 more source

Alterations in intestinal permeability [PDF]

Gut, 2006
The goal of this review is to describe barrier function of the intestine, the structure of the tight junction, methods to evaluate intestinal permeability, and most importantly the relevance of abnormal permeability to disease. In this context, we will also present an emerging paradigm regarding the genesis of autoimmune diseases and describe the data ...
M C, Arrieta, L, Bistritz, J B, Meddings
openaire   +2 more sources

Improvement of gut microbiome and intestinal permeability following splenectomy plus pericardial devascularization in hepatitis B virus-related cirrhotic portal hypertension

Frontiers in Immunology, 2022
The gut microbiome is an essential component of the intestinal mucosal barrier, critical in regulating intestinal permeability. Microbiome dysbiosis and intestinal permeability changes are commonly encountered conditions in patients with cirrhosis and ...
Yang Zhao, Yang Zhao, Rui Zhou, Rui Zhou, Ying Guo, Ying Guo, Xi Chen, Xi Chen, Aiyu Zhang, Aiyu Zhang, Jiayin Wang, Fanpu Ji, Fanpu Ji, Fanpu Ji, Bowen Qin, Bowen Qin, Jing Geng, Jing Geng, Guangyao Kong, Guangyao Kong, Zongfang Li, Zongfang Li, Zongfang Li   +22 more
doaj   +1 more source

Gliadin, zonulin and gut permeability: effects on celiac and non-celiac intestinal mucosa and intestinal cell lines. [PDF]

, 2006
OBJECTIVE: Little is known about the interaction of gliadin with intestinal epithelial cells and the mechanism(s) through which gliadin crosses the intestinal epithelial barrier. We investigated whether gliadin has any immediate effect on zonulin release
Carroccio A, Catassi C, CLEMENTE, MARIA GRAZIA, D'Agate C, Di Pierro M, Drago S, El Asmar R, Fasano A., Iacono G, Not T, Sapone A, Thakar M, Tripathi A, Zampini L   +13 more
core   +1 more source

Enhancement of prostaglandin D2-D prostanoid 1 signaling reduces intestinal permeability by stimulating mucus secretion

Frontiers in Immunology, 2023
IntroductionThe intestinal barrier plays a crucial role in distinguishing foods from toxins. Prostaglandin D2 (PGD2) is one of the lipid-derived autacoids synthesized from cell membrane-derived arachidonic acid.
Akane Hayashi, Naoaki Sakamoto, Koji Kobayashi, Takahisa Murata, Takahisa Murata, Takahisa Murata   +5 more
doaj   +1 more source

TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. [PDF]

PLoS ONE, 2011
Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn's disease and ...
Lauren E Kolodziej, James P Lodolce, Jonathan E Chang, Jeffrey R Schneider, Wesley A Grimm, Sarah J Bartulis, Xiaorong Zhu, Jeannette S Messer, Stephen F Murphy, Nishith Reddy, Jerrold R Turner, David L Boone   +11 more
doaj   +1 more source

Laminaria japonica Extract Enhances Intestinal Barrier Function by Altering Inflammatory Response and Tight Junction-Related Protein in Lipopolysaccharide-Stimulated Caco-2 Cells. [PDF]

, 2019
In the normal physiological state, intestinal epithelial cells act as a defensive frontline of host mucosal immunity to tolerate constant exposure to external stimuli.
Ding, Eom, Fawaz G Haj, Folin, Guiguo Zhang, Heo, Hyo-Seon Yang, Inhae Kang, Myoungsook Lee, Shirosaki, Shon, Wells, Wolfrom, Yunkyoung Lee   +13 more
core   +1 more source

Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]

, 2020
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L., Battaglia, R., Bruno, G., Ciardi, M. R., Corazziari, E. S., de Angelis, M., Iera, J., Mascellino, M. T., Mastroianni, C. M., Miele, M. C., Morelli, S., Oliva, A., Venditti, M., Vullo, V.   +13 more
core   +1 more source