Results 261 to 270 of about 128,505 (309)

BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells. [PDF]

open access: yesEMBO J
Li Y   +12 more
europepmc   +1 more source

Intestinal stem cells and intestinal organoids

Journal of Genetics and Genomics, 2020
The intestinal epithelium is one of the most rapidly renewing tissues, which is fueled by stem cells at the base of the crypts. Strategies of genetic lineage tracing and organoids, which capture major features of original tissues, are powerful avenues for exploring the biology of intestinal stem cells in vivo and in vitro, respectively. The combination
Qian, Zhao, Jiawei, Guan, Xia, Wang
openaire   +2 more sources

Intestinal Stem Cells

Journal of Pediatric Gastroenterology and Nutrition, 2009
ABSTRACTThe epithelial cell lining of the gastrointestinal tract is the most rapidly proliferating tissue in the body. The constant state of renewal of differentiated epithelial cells is sustained by a continual supply of progeny from multipotent progenitors that originate from stem cells located within the intestinal crypts.
Aaron P, Garrison   +2 more
openaire   +2 more sources

Small intestinal stem cells

Current Opinion in Gastroenterology, 2013
To summarize our current understanding of small intestinal stem cell biology and the current tools available for studying intestinal stem cells (ISCs).Recent reviews and original reports point toward the presence of two distinct populations of stem cells (ISCs) within the intestinal crypts.
Stephanie L, King   +1 more
openaire   +2 more sources

Intestinal stem cell transplantation

Journal of Gastroenterology, 2016
Organoid technologies to expand intestinal epithelial cells are gaining increasing attention as a useful tool to investigate many aspects of intestinal epithelial biology and pathology. One important application of organoid systems would be to use intestinal epithelial cells expanded in culture for following transplantation experiments. In this article,
Tetsuya, Nakamura, Mamoru, Watanabe
openaire   +2 more sources

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