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The exosome journey: from biogenesis to uptake and intracellular signalling
Cell communication and signaling : CCS, 2021 The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials testing exosomes for diagnostic and therapeutic applications are generating remarkable interest from the scientific community and investors.
Sonam Gurung +3 more
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Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors
Science, 2023 Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric diseases, and the ability to promote cortical neuron growth has been hypothesized to underlie the rapid and sustained therapeutic effects of psychedelics ...
Maxemiliano V. Vargas +13 more
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Effect of topical use of solution containing ferrous ions on treatment efficacy in women with recurrent urogenital trichomoniasis [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2022 Objective. To assess effect of topical use of solution containing ferrous ions on efficacy of metronidazole therapy in women with recurrent urogenital trichomoniasis. Materials and Methods.
Cherkasova Yu.I. +3 more
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Complosome — the intracellular complement system
Nature Reviews Nephrology, 2023 The complement system is a recognized pillar of host defence against infection and noxious self-derived antigens. Complement is traditionally known as a serum-effective system, whereby the liver expresses and secretes most complement components, which ...
E. West, C. Kemper
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Multifunctional intracellular matrix metalloproteinases: implications in disease
The FEBS Journal, 2021 Matrix metalloproteinases (MMPs) are zinc‐dependent endopeptidases that were first discovered as proteases, which target and cleave extracellular proteins. During the past 20 years, however, intracellular roles of MMPs were uncovered and research on this
Wesam Bassiouni, M. Ali, R. Schulz
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The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Science, 2020 Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear.
D. Nejman +60 more
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Selective autophagy of intracellular organelles: recent research advances
Theranostics, 2021 Macroautophagy (hereafter called autophagy) is a highly conserved physiological process that degrades over-abundant or damaged organelles, large protein aggregates and invading pathogens via the lysosomal system (the vacuole in plants and yeast ...
Wen Li +25 more
semanticscholar +1 more source
GUT MICROSYMBIOCENOSIS IN CHILDREN WITH REACTIVE ARTHRITIS
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. To study the state of gut microsymbiocenosis in children with reactive arthritis (RA), with the assessment of biofilm formation (BFF) of microsymbionts and the ability to change cytokine levels (their anticytokine activity) in vitro.
O. V. Bukharin +9 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. Determination of distinctive parameters of the B. bifidum and B. longum genomes, which characterizes their adaptive potential applied to distal intestine biotope of the human gut. Materials and methods. 5 strains of bifidobacteria have been used: B.
S. V. Andryuschenko +4 more
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Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions.
Annual Review of Biophysics, 2020 Many biomolecular condensates appear to form via spontaneous or driven processes that have the hallmarks of intracellular phase transitions. This suggests that a common underlying physical framework might govern the formation of functionally and ...
Jeong-Mo Choi, A. Holehouse, R. Pappu
semanticscholar +1 more source