Results 101 to 110 of about 3,143,322 (333)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

PHENOTYPICAL CHARACTERISTICS AND GENETICAL DETERMINANTS OF PATHOGENICITY OF STAPHYLOCOCCUS AUREUS, ISOLATED FROM BACTERIAL CARRIERS, RESIDING ON THE TERRITORIES WITH VARIOUS LEVELS OF ANTHROPOGENIC POLLUTION OF AIR ENVIRONMENT

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Comparative phenotypical and genetical evaluation ofpathogenic potential of Staphylococcus aureus strains, isolated from resident bacterial carriers, residing on the territories with anthropogenic pollution of air environment of varying intensity ...
T. M Utkina   +4 more
doaj  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

ROLE OF BIOLOGICAL PROPERTIES OF CORYNEBACTERIA IN ASSOCIATIVE SYMBIOSIS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Microorganisms of the Corynebacterium genus are examined in the review as a component of a single microecological system of humans in the context of their interaction with the macroorganism, dominant and associative microorganisms under the conditions of
I. V Gladysheva, S. V Cherkasov
doaj  

A re-examination of Hebbian-covariance rules and spike timing-dependent plasticity in cat visual cortex in vivo

open access: yesFrontiers in Synaptic Neuroscience, 2010
Spike-Timing-Dependent Plasticity (STDP) is considered as an ubiquitous rule for associative plasticity in cortical networks in vitro. However, limited supporting evidence for its functional role has been provided in vivo.
Yves Frégnac   +7 more
doaj   +1 more source

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons

open access: yesNature Biomedical Engineering, 2019
Current electrophysiological or optical techniques cannot reliably perform simultaneous intracellular recordings from more than a few tens of neurons.
Jeffrey Abbott   +9 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells. [PDF]

open access: yes, 1996
Thymocytes must bind major histocompatibility complex (MHC) proteins on thymic epithelial cells in order to mature into either CD8+ cytotoxic T cells or CD4+ helper T cells.
Corbella, P   +5 more
core  

Predictable, Tunable Protein Production in Salmonella for Studying Host-Pathogen Interactions

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Here we describe the use of synthetic genetic elements to improve the predictability and tunability of episomal protein production in Salmonella. We used a multi-pronged approach, in which a series of variable-strength synthetic promoters were combined ...
Kendal G. Cooper   +4 more
doaj   +1 more source

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