Results 61 to 70 of about 791,437 (254)
Molecular Characterization of a Novel Intracellular ADP-Ribosyl Cyclase [PDF]
, 2007 Background. ADP-ribosyl cyclases are remarkable enzymes capable of catalyzing multiple reactions including the synthesis of the novel and potent intracellular calcium mobilizing messengers, cyclic ADP-ribose and NAADP.
Jonathan S Marchant +29 more
core +1 more source
Intracellular Ca2+ Regulation in Calcium Sensitive Phenotype of Saccharomyces cerevisiae
Hayati Journal of Biosciences, 2010 Intracellular cytosolic Ca2+ concentration accumulation plays an essential information in Saccharomyces cerevisiae i.e. to explain cellular mechanism of Ca2+ sensitive phenotype. Disruption both S. cerevisiae PPase PTP2 and MSG5 genes showed an inhibited
HERMANSYAH
doaj +3 more sources
Ca2+ Measurements in Mammalian Cells with Aequorin-based Probes
Bio-Protocol, 2017 Aequorin is a Ca2+ sensitive photoprotein suitable to measure intracellular Ca2+ transients in mammalian cells. Thanks to recombinant cDNAs expression, aequorin can be specifically targeted to various subcellular compartments, thus allowing an accurate ...
Anna Tosatto +2 more
doaj +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]
, 1992 We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J. +3 more
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Copine‐4 Paraneoplastic Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang +12 more
wiley +1 more source
Dissecting novel regulatory mechanisms of S100A1 on cardiac function [PDF]
, 2007 6.1 Extracellular S100A1 inhibits apoptosis in ventricular cardiomyocytes: via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2) Growing evidence indicates that members of the S100 protein family exert intracellular but ...
Börries, Melanie
core +1 more source
Journal of Pharmacological Sciences, 2006 Many kinds of vasodilators induce relaxation of the vascular smooth muscle cells (VSMCs) through the production of cyclic AMP (cAMP) or cyclic GMP (cGMP).
Junji Nishimura
doaj +1 more source
Advanced Functional Materials, EarlyView.Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley +1 more source
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3 [PDF]
, 2008 Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (SCA3, MJD1) protein.
X. Chen +15 more
core +1 more source