Results 1 to 10 of about 289,046 (190)

Chloride channels of intracellular membranes [PDF]

open access: yesFEBS Letters, 2010
Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a
Christina Ross Kahl, John C. Edwards
openaire   +3 more sources

TRP channels of intracellular membranes [PDF]

open access: yesJournal of Neurochemistry, 2010
J. Neurochem. (2010) 113, 313–328.AbstractIon channels are classically understood to regulate the flux of ions across the plasma membrane in response to a variety of environmental and intracellular cues. Ion channels serve a number of functions in intracellular membranes as well.
Dong, Xian-Ping   +2 more
openaire   +4 more sources

Mechanisms associated with activation of intracellular metabotropic glutamate receptor, mGluR5 [PDF]

open access: yes, 2016
The group 1 metabotropic glutamate receptor, mGluR5, is found on the cell surface as well as on intracellular membranes where it can mediate both overlapping and unique signaling effects.
Jong, Yuh-Jiin I, O\u27Malley, Karen L
core   +2 more sources

Alternate routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4 [PDF]

open access: yes, 2015
Insulin-stimulated delivery of glucose transporters (GLUT4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose.
Bryant, Nia J.   +3 more
core   +3 more sources

Monitoring voltage fluctuations of intracellular membranes [PDF]

open access: yesScientific Reports, 2018
AbstractIn eukaryotic cells, the endoplasmic reticulum (ER) is the largest continuous membrane-enclosed network which surrounds a single lumen. Using a new genetically encoded voltage indicator (GEVI), we applied the patch clamp technique to cultured HEK293 cells and neurons and found that there is a very fast electrical interaction between the plasma ...
Bradley J. Baker   +5 more
openaire   +4 more sources

Fission of a multiphase membrane tube [PDF]

open access: yes, 2004
A common mechanism for intracellular transport is the use of controlled deformations of the membrane to create spherical or tubular buds. While the basic physical properties of homogeneous membranes are relatively well-known, the effects of ...
A. Roux   +14 more
core   +6 more sources

Intracellular mGluR5 plays a critical role in neuropathic pain [PDF]

open access: yes, 2016
Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here
Bandegi, Pouya   +10 more
core   +2 more sources

Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]

open access: yes, 2015
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki   +4 more
core   +2 more sources

A lysozyme-like protein in Brucella abortus is involved in the early stages of intracellular replication [PDF]

open access: yes, 2013
Secretion of proteins in Gram-negative bacteria is a high-energy consuming process that requires the translocation across two membranes and a periplasmic space composed of a mesh like layer, the peptidoglycan.
Czibener, Cecilia   +2 more
core   +1 more source

Duramycin-induced calcium release in cancer cells [PDF]

open access: yes, 2015
Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood.
Broughton, Laura J.   +3 more
core   +1 more source

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