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Monitoring voltage fluctuations of intracellular membranes [PDF]

open access: yesScientific Reports, 2018
In eukaryotic cells, the endoplasmic reticulum (ER) is the largest continuous membrane-enclosed network which surrounds a single lumen. Using a new genetically encoded voltage indicator (GEVI), we applied the patch clamp technique to cultured HEK293 ...
Masoud Sepehri Rad   +3 more
doaj   +5 more sources

Inducible intracellular membranes: molecular aspects and emerging applications [PDF]

open access: yesMicrobial Cell Factories, 2020
Membrane remodeling and phospholipid biosynthesis are normally tightly regulated to maintain the shape and function of cells. Indeed, different physiological mechanisms ensure a precise coordination between de novo phospholipid biosynthesis and ...
Jorge Royes   +4 more
doaj   +2 more sources

Ectopic Neo-Formed Intracellular Membranes in Escherichia coli: A Response to Membrane Protein-Induced Stress Involving Membrane Curvature and Domains [PDF]

open access: yesBiomolecules, 2018
Bacterial cytoplasmic membrane stress induced by the overexpression of membrane proteins at high levels can lead to formation of ectopic intracellular membranes.
Nadège Jamin   +4 more
doaj   +2 more sources

Differential increase in endocannabinoid levels at the plasma and intracellular membranes [PDF]

open access: yesiScience
Summary: Endocannabinoids (eCBs) modulate the activity of proteins expressed at the plasma and intracellular membranes. Nothing is known about the dynamic changes in eCB levels in these subcellular compartments.
Simar Singh   +8 more
doaj   +2 more sources

Compartmentalized GPCR Signaling from Intracellular Membranes. [PDF]

open access: yesJ Membr Biol, 2021
G protein-coupled receptors (GPCRs) are integral membrane proteins that transduce a wide array of inputs including light, ions, hormones, and neurotransmitters into intracellular signaling responses which underlie complex processes ranging from vision to learning and memory.
Crilly SE, Puthenveedu MA.
europepmc   +3 more sources

Gαi3-dependent inhibition of JNK activity on intracellular membranes [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Heterotrimeric G-protein signalling has been shown to modulate a wide variety of intracellular signalling pathways including the mitogen-activated protein kinase (MAPK) family.
Guillaume eBastin   +2 more
doaj   +2 more sources

Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation [PDF]

open access: yeseLife, 2022
The formation of a clathrin-coated vesicle (CCV) is a major membrane remodeling process that is crucial for membrane traffic in cells. Besides clathrin, these vesicles contain at least 100 different proteins although it is unclear how many are essential ...
Cansu Küey   +4 more
doaj   +2 more sources

Chloride channels of intracellular membranes. [PDF]

open access: yesFEBS Lett, 2010
Proteins implicated as intracellular chloride channels include the intracellular ClC proteins, the bestrophins, the cystic fibrosis transmembrane conductance regulator, the CLICs, and the recently described Golgi pH regulator. This paper examines current hypotheses regarding roles of intracellular chloride channels and reviews the evidence supporting a
Edwards JC, Kahl CR.
europepmc   +4 more sources

TRP channels of intracellular membranes. [PDF]

open access: yesJ Neurochem, 2010
J. Neurochem. (2010) 113, 313–328.AbstractIon channels are classically understood to regulate the flux of ions across the plasma membrane in response to a variety of environmental and intracellular cues. Ion channels serve a number of functions in intracellular membranes as well.
Dong XP, Wang X, Xu H.
europepmc   +5 more sources

Mutual Mobile Membranes with Timers [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2009
A feature of current membrane systems is the fact that objects and membranes are persistent. However, this is not true in the real world. In fact, cells and intracellular proteins have a well-defined lifetime.
Gabriel Ciobanu, Bogdan Aman
doaj   +4 more sources

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