Results 11 to 20 of about 2,828,883 (298)

Self and non-self discrimination of intracellular membranes by the innate immune system. [PDF]

open access: yesPLoS Pathog, 2013
To discriminate self from non-self, the innate immune system evolved a large repertoire of germline-encoded receptors that detect molecular patterns associated with infections [1].
Coers J.
europepmc   +2 more sources

Gαi3-dependent inhibition of JNK activity on intracellular membranes [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Heterotrimeric G-protein signalling has been shown to modulate a wide variety of intracellular signalling pathways including the mitogen-activated protein kinase (MAPK) family.
Guillaume eBastin   +2 more
doaj   +2 more sources

Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation [PDF]

open access: yeseLife, 2022
The formation of a clathrin-coated vesicle (CCV) is a major membrane remodeling process that is crucial for membrane traffic in cells. Besides clathrin, these vesicles contain at least 100 different proteins although it is unclear how many are essential ...
Cansu Küey   +4 more
doaj   +2 more sources

Mutual Mobile Membranes with Timers [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2009
A feature of current membrane systems is the fact that objects and membranes are persistent. However, this is not true in the real world. In fact, cells and intracellular proteins have a well-defined lifetime.
Gabriel Ciobanu, Bogdan Aman
doaj   +2 more sources

Essentially all excess fibroblast cholesterol moves from plasma membranes to intracellular compartments. [PDF]

open access: yesPLoS ONE, 2014
It has been shown that modestly increasing plasma membrane cholesterol beyond its physiological set point greatly increases the endoplasmic reticulum and mitochondrial pools, thereby eliciting manifold feedback responses that return cell cholesterol to ...
Yvonne Lange, Jin Ye, Theodore L Steck
doaj   +2 more sources

Mesenchymal Stem/Stromal Cells in Three-Dimensional Cell Culture: Ion Homeostasis and Ouabain-Induced Apoptosis

open access: yesBiomedicines, 2023
This study describes the changes in ion homeostasis of human endometrial mesenchymal stem/stromal cells (eMSCs) during the formation of three-dimensional (3D) cell structures (spheroids) and investigates the conditions for apoptosis induction in 3D eMSCs.
Alla N. Shatrova   +4 more
doaj   +1 more source

Proteins Related to the Type I Secretion System Are Associated with Secondary SecA_DEAD Domain Proteins in Some Species of Planctomycetes, Verrucomicrobia, Proteobacteria, Nitrospirae and Chlorobi. [PDF]

open access: yesPLoS ONE, 2015
A number of bacteria belonging to the PVC (Planctomycetes-Verrucomicrobia-Chlamydiae) super-phylum contain unusual ribosome-bearing intracellular membranes. The evolutionary origins and functions of these membranes are unknown.
Olga K Kamneva   +2 more
doaj   +1 more source

Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle

open access: yesVeterinary Sciences, 2020
Ca2+ regulation in equine muscle is important for horse performance, yet little is known about this species-specific regulation. We reported recently that horse encode unique gene and protein sequences for the sarcoplasmic reticulum (SR) Ca2 ...
Joseph M. Autry   +6 more
doaj   +1 more source

LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells

open access: yesCells, 2020
The cardiovascular disease (CVD) frequently developed during metabolic syndrome and type-2 diabetes mellitus is associated with increased levels of aggregation-prone small LDL particles.
Virginia Actis Dato   +6 more
doaj   +1 more source

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