Results 321 to 330 of about 281,844 (353)

Heterogeneity of intracellular replication of bacterial pathogens

Current Opinion in Microbiology, 2013
Intracellular growth of bacterial pathogens is usually measured at the whole population level, which masks potential cell-to-cell variation. More direct measurements of replication using microscopy and Flow Cytometry have revealed extensive heterogeneity among populations of intracellular bacteria.
Sophie, Helaine, David W, Holden
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Protective immunity towards intracellular pathogens

Current Opinion in Immunology, 2006
Immunity towards intracellular pathogens is often dependent upon the generation of CD8(+) memory T cells, which provide long-lasting and effective protection. Over the past few years, we have gained novel insights into the heterogeneity of CD8(+) T cells, time points of lineage commitment, and lineage relationships between subpopulations. These studies
Katharina M, Huster, Christian, Stemberger, Dirk H, Busch   +2 more
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Nanocarriers with Gentamicin to Treat Intracellular Pathogens

Journal of Nanoscience and Nanotechnology, 2006
Brucellosis is a worldwide zoonosis caused by different species of the genus Brucella. The intracellular localisation of this pathogen, particularly in macrophages, renders treatment difficult since most antibiotics known to be efficient in vitro do not actively pass through cellular membranes.
C, Lecaroz, C, Gamazo, M J, Blanco-Prieto   +2 more
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Phenotypic modulation by intracellular bacterial pathogens

Electrophoresis, 1999
Microorganisms have the capacity to sense their environment and to respond to it by alteration in gene expression and protein synthesis. Two-dimensional electrophoresis (2-DE) provides a powerful tool to examine the global response in bacterial protein synthesis upon exposure to different environmental signals.
Y A, Kwaik, O S, Harb
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Genetic regulation of resistance to intracellular pathogens

Nature, 1982
Natural resistance of mice to infections with Salmonella typhimurium and Leishmania donovani is regulated by chromosome 1 gene(s) designated Ity and Lsh, respectively1,2. Given the fact that these two microorganisms are taxonomically and antigenically distinct, and yet the host response to them is regulated by the same locus or complex3,4, one might ...
Skamene, E, Gros, P, Forget, A, Kongshavn, P A, St, Charles C, Taylor, B A   +5 more
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Host Resistance Model to an Intracellular Pathogen

Current Protocols in Toxicology, 2006
AbstractThis unit describes a model for the determination of host resistance in mice using a Gram‐positive intracellular bacterium, Listeria monocytogenes (LM), and discusses its broad use in immunotoxicological studies. The provides detailed procedures for LM infection and sample analysis, including preparation and infection of mice with LM ...
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PATHOGENICITY OF MYCOBACTERIUM INTRACELLULARE TO PIGS

Australian Veterinary Journal, 1971
SummaryThe pathologic response of pigs to a strain of M. intracellulare serotype VI was investigated in three trials. Ten mg wet weight of the second subculture maintained on Löwenstein‐Jensen slopes produced a large number of tubercular nodules in the mesenteric lymph node of one pig infected orally, and similar lesions in the iliac lymph nodes of ...
L, Tammemagi, G C, Simmons
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Strategies for the eradication of intracellular bacterial pathogens

Biomaterials Science
Representative antimicrobial delivery platforms and strategies for the eradication of intracellular bacterial pathogens.
Yingying Chen, Yunjiang Jiang, Tianrui Xue, Jianjun Cheng   +3 more
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Is Salmonella an Intracellular Pathogen?

1993
My assigned topic of presentation in this Workshop is to address the issue of whether Salmonella is an intracellular pathogen. The simple answer to that question is yes and no, depending on the host cells into which the pathogen has entered. There are many of us here in this Workshop who are studying the genetic factors governing the invasive or ...
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Autophagy as a defence against intracellular pathogens

Essays in Biochemistry, 2013
Autophagy is a membrane trafficking pathway that results in the formation of autophagosomes which deliver portions of the cytosol to lysosomes for degradation. When autophagosomes engulf intracellular pathogens, the pathway is called ‘xenophagy’ because it leads to the removal of foreign material.
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