Results 21 to 30 of about 1,288,434 (306)

Carboxyamidotriazole reduces programmed cell death 1 expression by inhibiting NFAT2 nuclear transport in murine CD8+T cells [PDF]

Jichu yixue yu linchuang, 2020
Objective To study the effect of carboxyamidotriazole (CAI) on CD8+T cells, and to explore the critical mechanism of CAI in reinforcing cytotoxicity of activated T cells. Methods CD8+T cells of mouse were isolated by immunomagnetic beads and divided into
XU Meng-jiao, GAO Hong-ting, SHI Jing, JU Rui, YANG Li-xing, LI Jian-heng, GUO Lei
doaj  

Transcriptional response to the host cell environment of a multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features

Scientific Reports, 2021
Tuberculosis is a global public health problem with emergence of multidrug-resistant infections. Previous epidemiological studies of tuberculosis in Thailand have identified a clonal outbreak multidrug-resistant strain of Mycobacterium tuberculosis in ...
Pakorn Aiewsakun, Pinidphon Prombutara, Tegar Adriansyah Putra Siregar, Thanida Laopanupong, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Suparerk Borwornpinyo, Pirut Tong-Ngam, Alisa Tubsuwan, Prapaporn Srilohasin, Angkana Chaiprasert, Wuthiwat Ruangchai, Prasit Palittapongarnpim, Therdsak Prammananan, Brian C. VanderVen, Marisa Ponpuak   +15 more
doaj   +1 more source

Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation

Journal of Extracellular Vesicles, 2022
Extracellular vesicles (EVs) have been proved a promising small interfering RNA (siRNA) delivery vehicle to mediate gene‐silencing. Tumour‐derived extracellular vesicles (TDEVs) as genetic exchange vectors in the tumour microenvironment, enable ...
Xin Zhou, Yunqiu Miao, Ying Wang, Shufang He, Linmiao Guo, Junsong Mao, Mingshu Chen, Yuting Yang, Xinxin Zhang, Yong Gan   +9 more
doaj   +1 more source

Lipoaspirate stored at a constant low temperature by electric control suppresses intracellular metabolism and maintains high cell viability

Regenerative Therapy, 2023
Background: Cell therapy is a useful treatment method for wide spectrum of diseases which utilizes the immunosuppressive and regenerative abilities of administered cells.
Ryoko Inaki, Yoshihiko Sato, Daisuke Nakamura, Yoshiyuki Aikawa, Tsuyoshi Takato, Kazuto Hoshi, Atsuhiko Hikita   +6 more
doaj   +1 more source

Real-time visualization of clustering and intracellular transport of gold nanoparticles by correlative imaging

Nature Communications, 2017
The interaction of nanoparticles intracellularly has been investigated widely but the mechanisms of such interactions are not fully understood. Here, the authors utilize a semi-quantitative technique to assess the intracellular transportation and ...
Mengmeng Liu, Qian Li, Le Liang, Jiang Li, Kun Wang, Jiajun Li, Min Lv, Nan Chen, Haiyun Song, Joon Lee, Jiye Shi, Lihua Wang, Ratnesh Lal, Chunhai Fan   +13 more
doaj   +1 more source

Intracellular Penetration and Effects of Antibiotics on Staphylococcus aureus Inside Human Neutrophils: A Comprehensive Review

Antibiotics, 2019
Neutrophils are important assets in defense against invading bacteria like staphylococci. However, (dysfunctioning) neutrophils can also serve as reservoir for pathogens that are able to survive inside the cellular environment. Staphylococcus aureus is a
Suzanne Bongers, Pien Hellebrekers, Luke P.H. Leenen, Leo Koenderman, Falco Hietbrink   +4 more
doaj   +1 more source

Synergistic Effect of Hydrogen Peroxide and Cold Atmospheric Pressure Plasma-Jet for Microbial Disinfection

Applied Sciences, 2023
The efficiency of simultaneous treatment of the cold atmospheric pressure plasma jet (CAP) and hydrogen peroxide (H2O2) was investigated. A CAP with a thin and long plume was generated with Ar gas and applied to a common oral bacterium, Enterococcus ...
Ku Youn Baik, Hyun Jo, Se Hoon Ki, Gi-Chung Kwon, Guangsup Cho   +4 more
doaj   +1 more source

Intracellular compartmentation and transport of metabolites [PDF]

Journal of Supramolecular Structure, 1978
AbstractThe intracellular locations of enzymes and metabolites were determined for ornithine metabolism in Neurospora. Pulse label experiments were used to measure the rates of intracellular translocations and the sizes of compartmented pools of metabolites in the mitochondrial, cytosolic and vesicular compartments.
Davis, Rowland H, Bowman, Barry J, Weiss, Richard L   +2 more
openaire   +4 more sources

S100 Proteins As an Important Regulator of Macrophage Inflammation

Frontiers in Immunology, 2018
The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of intracellular and extracellular functions through regulating calcium balance, cell apoptosis, migration, proliferation, differentiation, energy metabolism, and ...
Chang Xia, Chang Xia, Zachary Braunstein, Amelia C. Toomey, Jixin Zhong, Xiaoquan Rao   +5 more
doaj   +1 more source

Intracellular transport by active diffusion [PDF]

Trends in Cell Biology, 2009
All substances exhibit constant random motion at the microscopic scale. This is a direct consequence of thermal agitation, and leads to diffusion of molecules and small particles in a liquid. In addition to this nondirected motion, living cells also use active transport mechanisms, such as motor activity and polymerization forces that depend on linear ...
Brangwynne, C. P., Koenderink, G.H., Mac Kintosh, F.C., Weitz, D. A.   +3 more
openaire   +3 more sources