Results 41 to 50 of about 1,288,434 (306)

Intracellular Assessment of ATP Levels in Caenorhabditis elegans

open access: yesBio-Protocol, 2016
Eukaryotic cells heavily depend on adenosine triphosphate (ATP) generated by oxidative phosphorylation (OXPHOS) within mitochondria. ATP is the major energy currency molecule, which fuels cell to carry out numerous processes, including growth ...
Konstantinos Palikaras   +1 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Cationic Nanoparticles Assembled from Natural-Based Steroid Lipid for Improved Intracellular Transport of siRNA and pDNA

open access: yesNanomaterials, 2016
Developing new functional biomaterials from biocompatible natural-based resources for gene/drug delivery has attracted increasing attention in recent years.
Ruilong Sheng   +5 more
doaj   +1 more source

Barcoding Hedgehog for Intracellular Transport [PDF]

open access: yesScience Signaling, 2011
Cholesterol modification may alter the intracellular localization of Hedgehog, thereby influencing where Hedgehog is released.
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Plasma Membrane Targeting of Protocadherin 15 Is Regulated by the Golgi-Associated Chaperone Protein PIST

open access: yesNeural Plasticity, 2016
Protocadherin 15 (PCDH15) is a core component of hair cell tip-links and crucial for proper function of inner ear hair cells. Mutations of PCDH15 gene cause syndromic and nonsyndromic hearing loss.
Hongyun Nie   +7 more
doaj   +1 more source

Dync1li1 is required for the survival of mammalian cochlear hair cells by regulating the transportation of autophagosomes.

open access: yesPLoS Genetics, 2022
Dync1li1, a subunit of cytoplasmic dynein 1, is reported to play important roles in intracellular retrograde transport in many tissues. However, the roles of Dync1li1 in the mammalian cochlea remain uninvestigated.
Yuan Zhang   +9 more
doaj   +1 more source

Intracellular Copper Transport in Mammals [PDF]

open access: yesThe Journal of Nutrition, 2004
Copper is an essential cofactor for approximately a dozen cuproenzymes in which copper is bound to specific amino acid residues in an active site. However, free cuprous ions react readily with hydrogen peroxide to yield the deleterious hydroxyl radical.
Joseph R, Prohaska, Anna A, Gybina
openaire   +2 more sources

State Transportation Statistics 2015 [PDF]

open access: yes
The Bureau of Transportation Statistics (BTS) presents State Transportation Statistics 2015, a statistical profile of transportation in the 50 States and the District of Columbia.
Nguyen, Long X.   +2 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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