Results 71 to 80 of about 1,288,434 (306)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling

open access: yesNano-Micro Letters
Highlights Novel enzyme-induced proximity labeling technology in nanoparticles (nano-EPL). Nano-EPL enables dynamic molecular mapping of the intracellular delivery of nanoparticles in macrophages.
Junji Ren   +10 more
doaj   +1 more source

Intracellular sorting and transport of proteins

open access: yesProgress in Biophysics and Molecular Biology, 2003
The secretory and endocytic pathways of eukaryotic organelles consist of multiple compartments, each with a unique set of proteins and lipids. Specific transport mechanisms are required to direct molecules to defined locations and to ensure that the identity, and hence function, of individual compartments are maintained. The localisation of proteins to
van Vliet, Catherine   +4 more
openaire   +5 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

An antifouling membrane-fusogenic liposome for effective intracellular delivery in vivo

open access: yesNature Communications
The membrane-fusion-based internalization without lysosomal entrapment is advantageous for intracellular delivery over endocytosis. However, protein corona formed on the membrane-fusogenic liposome surface converts its membrane-fusion performance to ...
Huimin Kong   +6 more
doaj   +1 more source

Annual Report for Calendar Year 2017: New England Transportation Consortium [PDF]

open access: yes
The New England Transportation Consortium (NETC) is a cooperative effort of the transportation agencies of the six New England States, the six New England state land grant universities, and the Federal Highway Administration (FHWA).
New England Transportation Consortium
core  

Transportation Expressions

open access: yes
This report compiles definitions of transportation terms used throughout the Department of Transportation and other US government agencies. This is the first edition of Transportation Expressions; future editions will be expanded in scope to include ...
O'Leary, Pamela   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A hypothetical model of crossing Bombyx mori nucleopolyhedrovirus through its host midgut physical barrier.

open access: yesPLoS ONE, 2014
Bombyx mori nucleopolyhedrovirus (BmNPV) is a primary pathogen of silkworm (B. mori) that causes severe economic losses each year. However, the molecular mechanisms of silkworm-BmNPV interactions, especially the silkworm proteins that can interact with ...
Yang Cheng   +4 more
doaj   +1 more source

Host Factors Involved in the Intracellular Movement of Bamboo mosaic virus

open access: yesFrontiers in Microbiology, 2017
Viruses move intracellularly to their replication compartments, and the newly synthesized viral complexes are transported to neighboring cells through hijacking of the host endomembrane systems.
Chi-Ping Cheng
doaj   +1 more source

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