Results 121 to 130 of about 28,196 (246)

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Are Postprandial Bile Acid Levels Helpful in Predicting Perinatal Complications in Patients with Intrahepatic Cholestasis of Pregnancy?

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: To determine the outcomes of Iintrahepatic cholestasis of pregnancy and the role of postprandial serum bile acid levels in the prediction of perinatal complications.
Kudret Erkenekli, Can Tekin iskender, Hasan Onur Topcu, Tugba Ensari, Dilek Uygur, Nuri Danisman   +5 more
doaj  

Monochorionic twin pregnancies conceived through assisted reproduction: Maternal and perinatal clinical outcomes

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 868-877, May 2026.
ART‐conceived monochorionic twin pregnancies are associated with a higher burden of maternal complications compared with spontaneous conception. While fetal and neonatal outcomes did not differ significantly between groups after adjustment for relevant confounders, ART‐conceived pregnancies showed higher point estimates for several adverse outcomes ...
Daniela Casati, Mariano M. Lanna, Arianna Laoreti, Stefano Faiola, Roberta Morelli, Martina Santapaola, Gianluca Lista, Valeria Savasi   +7 more
wiley   +1 more source

Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.
Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg, Jesus M. Banales, Gideon Hirschfield, Palak Trivedi, Edward E. Cable, Charles A. McWherter, Andrew N. Billin, Daria B. Crittenden, Grant Budas   +8 more
wiley   +1 more source

The bile salt export pump [PDF]

, 2018
Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow.
Meier, Peter, Meier, Yvonne, Stieger, Bruno   +2 more
core  

Intrahepatic cholestasis of pregnancy

Canadian Medical Association Journal, 2022
Hobson, Sebastian, Gandhi, Shital, Sobel, Mara   +2 more
openaire   +2 more sources

A Retrospective Multicenter Study Identifies a Similar Overall Survival of Patients After Liver Transplantation With Incidental Cholangiocarcinoma Compared to Hepatocellular Carcinoma

Clinical Transplantation, Volume 40, Issue 5, May 2026.
ABSTRACT Background Cholangiocarcinoma (CCA) is the second most common liver malignancy with a dismal prognosis. Liver transplantation of patients with CCA is currently no treatment option backed by guidelines for most of the patients, mainly because of presumably worse outcome.
Sophia Heinrich, Alejandro Campos‐Murguia, Angelina Mensah, Kateryna Shmanko, Dionysios Koliogiannis, Kathrin H. Vollmann, Simone C. Boedecker‐Lips, Bernd Heinrich, Theresa Kirchner, Bastian Engel, Christian M. Lange, Arndt Weinmann, Jens Mittler, Thomas C. Wirth, Anna Saborowski, Heiner Wedemeyer, Richard Taubert   +16 more
wiley   +1 more source

The Risk Factors for Placental Abruption in Preeclamptic Pregnancies: A Retrospective Case–Control Study

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Preeclampsia poses a high‐risk factor for placental abruption. The precise understanding of the accompanying symptoms and disease phenotype of preeclampsia, in order to promptly identify the occurrence of placental abruption in preeclamptic women, remains unclear.
Kechen Li, Qiaoqiao Lin, Anjian Xu, Jieni Zou, Li Zhou, Ying Hua, Qianmeng Huang   +6 more
wiley   +1 more source

Intrahepatic cholestasis of pregnancy : genetic background, epidemiology and hepatobiliary consequences [PDF]

, 2006
Intrahepatic cholestasis of pregnancy (ICP) is the most common cholestatic liver disease during pregnancy. The reported incidence varies from 0.4 to 15% of full-term pregnancies.
Ropponen, Anne
core