Results 131 to 140 of about 28,196 (246)

Baseline Alkaline Phosphatase Impacts Response Rates in Primary Biliary Cholangitis: Exploring Response to Elafibranor in ELATIVE

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background & Aims Baseline alkaline phosphatase (ALP) levels can influence the likelihood of achieving dichotomous biochemical response criteria in primary biliary cholangitis (PBC). This concept was explored using Week 52 data from the phase III ELATIVE trial (NCT04526665), which assessed elafibranor, a peroxisome proliferator‐activated ...
Cynthia Levy, Christopher L. Bowlus, Eric Lawitz, Nuno Antunes, Benjamin Miller, Jianfen Shu, Claudia O. Zein, Kris V. Kowdley   +7 more
wiley   +1 more source

Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70‐Deficient Mice With a Human‐Like Bile Acid Composition

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Loss‐of‐function mutations in bile acid (BA)‐activated farnesoid x receptor (FXR/NR1H4) cause severe neonatal liver pathology in humans, earlier referred to as progressive familial intrahepatic cholestasis type 5 (PFIC5). However, Fxr‐deficient mice do not develop early‐onset liver disease, possibly due to the predominance ...
Hilde D. de Vries, Jinxiao Li, Kirill Ustyantsev, Milaine V. Hovingh, Niels L. Mulder, Rick Havinga, Anna Palmiotti, Krisztina de Bruyn, Brecht Attema, Ellen Weersing, Rachel E. Thomas, Vincent W. Bloks, Eugene Berezikov, Martijn van Faassen, Henkjan J. Verkade, Jan Freark de Boer, Folkert Kuipers   +16 more
wiley   +1 more source

Dermatoses Específicas da Gravidez [PDF]

, 2013
During pregnancy immunological, metabolic, hormonal and vascular changes occur, and can cause specific skin diseases. The specific dermatoses of pregnancy have undergone numerous changes in nomenclature and classification, partly due to advances in the ...
Coutinho, I, Gameiro, R, Gonçalo, Margarida, Teixieira, V, Vieira, R   +4 more
core  

Idiopathic adulthood ductopenia: long-term follow-up after liver transplantation [PDF]

, 2001
In 1988, Ludwig et al proposed the term idiopathic adulthood ductopenia (IAD) for the condition of chronic cholestatic liver disease associated with loss of intrahepatic bile ducts of unknown etiology with clinical onset in adulthood (1).
Herraiz-Bayod, M.J. (Maite J.), Herrero, J.I. (José Ignacio), Pardo, F. (Fernando), Prieto, J. (Jesús), Quiroga, J. (Jorge), Rios, R. (Raquel), Sangro, B. (Bruno), Sola, J. (Josu), Álvarez-Cienfuegos, J. (Javier)   +8 more
core  

Initial assessment of the infant with neonatal cholestasis--Is this biliary atresia? [PDF]

, 2017
et al.,, Turmelle, Yumirle P
core   +2 more sources

Effects of intraduodenally applied bile salts on pancreatic secretion [PDF]

, 1993
Lehnert, Peter, Riepl, Rudolf L.
core   +1 more source

Intrahepatic Cholestasis

Journal of Pediatric Gastroenterology and Nutrition, 2002
openaire   +3 more sources

Cholestatic liver disease in an adolescent: don't forget progressive familial intrahepatic Cholestasis-8. [PDF]

Oxf Med Case Reports
Lk P, Poyekar S, Gandhi D, Kalawadia S, Shah I.   +4 more
europepmc   +1 more source

A review of adult and pediatric post-transplant liver pathology. [PDF]

, 1987
Demetris, AJ, Jaffe, R, Starzl, TE
core  

Efficacy, Safety and Tolerability of Volixibat, an IBAT Inhibitor, in Patients With Intrahepatic Cholestasis of Pregnancy. [PDF]

Liver Int
Ovadia C, Stone S, Sibai B, Nunes T, Mogul DB, Krishnaswami J, Kahng J, Li F, Warsi QA, Chien E, Vig P, Williamson C.   +11 more
europepmc   +1 more source