Frequency and clinical variants of specific dermatoses in third trimester of pregnancy: a study from a tertiary care centre [PDF]
, 2012 OBJECTIVE: To determine the frequency of patients with dermatoses in the third trimester of pregnancy and to identify various clinical types of dermatoses in the third trimester. METHODS: The study was carried out at the Department of Dermatology and the
Akhtar, Shaheen +4 more
core +1 more source
Intrahepatic Cholestasis of Pregnancy: Risk Factor for Neonatal Respiratory Distress Syndrome? [PDF]
, 2013 Introdução: A colestase intra-hepática da gravidez está associada a complicações fetais e neonatais graves, incluindo síndrome de dificuldade respiratória.
Berenguer, A +6 more
core
Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor [PDF]
, 2013 Multidrug resistance–associated protein 3 (Mrp3; Abcc3) expression and activity are up-regulated in rat liver after in vivo repeated administration of ethynylestradiol (EE), a cholestatic synthetic estrogen, whereas multidrug resistance-associated ...
Arias, Agostina +7 more
core +2 more sources
Perinatal outcomes in normotensive versus hypertensive HELLP syndrome
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a tertiary university‐affiliated medical center including all singleton HELLP cases >24 weeks gestation (January ...
Matan Anteby +4 more
wiley +1 more source
Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis [PDF]
, 2009 Obstetric cholestasis (OC) is a serious problem in pregnancy. It affects about 4500 women per year in the UK. Affected women develop itching and occasionally jaundice.
Annette Briley +6 more
core +2 more sources
Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo +4 more
wiley +1 more source
European Journal of Case Reports in Internal MedicineIntroduction: Most pregnancies in women after a kidney transplant result in a live birth, but kidney functions should be stable for one year before conception. For immunosuppression modification occurring before pregnancy, azathioprine is used because it
Lamis Khedr, Mohamed Ekram
doaj +1 more source
New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications
Canadian Journal of Gastroenterology and Hepatology, 2018 Cholestasis is characterised by impaired bile secretion and accumulation of bile salts in the organism. Hereditary cholestasis is a heterogeneous group of rare autosomal recessive liver disorders, which are characterised by intrahepatic cholestasis ...
Eva Sticova +2 more
doaj +1 more source
Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta [PDF]
, 2019 Intrahepatic cholestasis of pregnancy (ICP) causes increased transfer of maternal bile acids to the fetus and an increased incidence of sudden fetal death.
Cleal, Jane K. +8 more
core +1 more source
Portal Hypertension &Cirrhosis, EarlyView.In this biopsy‐controlled study, FibroTouch and FibroScan demonstrated comparable diagnostic accuracy for liver fibrosis staging (AUROCs > 0.900), but FibroTouch required consistently higher stiffness thresholds. These discrepancies were more pronounced in patients with MAFLD, highlighting the need for device‐specific cutoffs to avoid misclassification.
Min Wang +8 more
wiley +1 more source