Results 81 to 90 of about 9,669 (210)

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth [PDF]

open access: yes, 2014
Epigenetic silencing through promoter hypermethylation is an important hallmark for the inactivation of tumor-related genes in carcinogenesis. Here we identified the ATP-binding cassette sub-family B member 4 (ABCB4) as a novel epigenetically silenced ...
Dammann, Reinhard H.   +7 more
core   +1 more source

Risk factors, predictive markers and prevention strategies for intrauterine fetal death. An integrative review [PDF]

open access: yes, 2020
According to World Health Organization (WHO), fetal death is defined as the death of the fetus prior to its complete expulsion, independent of the duration of pregnancy, thus only ascribing the term stillbirth to fetal deaths in the case of pregnancies ...
Andronache, Liliana Florina   +6 more
core   +2 more sources

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu   +8 more
wiley   +1 more source

Intrahepatic cholestasis of pregnancy

open access: yesCanadian Medical Association Journal, 2022
Hobson, Sebastian   +2 more
openaire   +3 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

Monochorionic twin pregnancies conceived through assisted reproduction: Maternal and perinatal clinical outcomes

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 5, Page 868-877, May 2026.
ART‐conceived monochorionic twin pregnancies are associated with a higher burden of maternal complications compared with spontaneous conception. While fetal and neonatal outcomes did not differ significantly between groups after adjustment for relevant confounders, ART‐conceived pregnancies showed higher point estimates for several adverse outcomes ...
Daniela Casati   +7 more
wiley   +1 more source

Association of ABCB4 and ABCB11 nucleotide variants with intrahepatic cholestasis of pregnancy

open access: yesJournal of Medical Science, 2019
Background. Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder during gestation. The exact pathogenesis of ICP is multifactorial and still unclear.
Milena Gruszczyńska-Losy   +5 more
doaj   +1 more source

Molecular mechanisms for fetal cardiac arrhythmia in intrahepatic cholestasis of pregnancy

open access: yes, 2010
Intrahepatic cholestasis in pregnancy (ICP) is characterized by raised serum bile acids which can cause fetal complications, including preterm labour and intrauterine death. The fetal death in ICP is not well understood. In this thesis, the mechanisms of
Sheikh Abdul Kadir, Siti Hamimah   +1 more
core   +1 more source

The Risk Factors for Placental Abruption in Preeclamptic Pregnancies: A Retrospective Case–Control Study

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Preeclampsia poses a high‐risk factor for placental abruption. The precise understanding of the accompanying symptoms and disease phenotype of preeclampsia, in order to promptly identify the occurrence of placental abruption in preeclamptic women, remains unclear.
Kechen Li   +6 more
wiley   +1 more source

A novel case report of benign recurrent intrahepatic cholestasis-associated USP53 genetic mutation in a Pakistani girl

open access: yesSAGE Open Medical Case Reports
Benign recurrent intrahepatic cholestasis is an autosomal recessive disorder presenting with intermittent episodes of cholestatic jaundice. The initial episode of benign recurrent intrahepatic cholestasis tends to occur within the first two decades of a ...
Tafiya Erum Kamran   +7 more
doaj   +1 more source

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