Results 1 to 10 of about 2,032 (137)

Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I [PDF]

Angewandte Chemie, 2017
AbstractIntramolecular benzoin reactions catalyzed by benzaldehyde lyase from Pseudomonas fluorescens biovar I (BAL) are reported. The structure of the substrates envisaged for this reaction consists of two benzaldehyde derivatives linked by an alkyl chain.
Karel Hernández, Teodor Parella, Giovanna Petrillo, Isabel Usón, Claudia M. Wandtke, Jesús Joglar, Jordi Bujons, Pere Clapés   +7 more
  +8 more sources

Bacterial Conversion of Hydroxylamino Aromatic Compounds by both Lyase and Mutase Enzymes Involves Intramolecular Transfer of Hydroxyl Groups [PDF]

Applied and Environmental Microbiology, 2003
ABSTRACT Hydroxylamino aromatic compounds are converted to either the corresponding aminophenols or protocatechuate during the bacterial degradation of nitroaromatic compounds. The origin of the hydroxyl group of the products could be the substrate itself (intramolecular transfer mechanism) or the solvent water (intermolecular ...
Zhongqi He, Lloyd J. Nadeau, Jim C. Spain   +2 more
openaire   +5 more sources

Molecular basis for azetidine-2-carboxylic acid biosynthesis [PDF]

Nature Communications
Azetidine-2-carboxylic acid (AZE) is a long-known plant metabolite. Recently, AZE synthases have been identified in bacterial natural product pathways involving non-ribosomal peptide synthetases.
Tim J. Klaubert, Jonas Gellner, Charles Bernard, Juliana Effert, Carine Lombard, Ville R. I. Kaila, Helge B. Bode, Yanyan Li, Michael Groll   +8 more
doaj   +2 more sources

Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights. [PDF]

PLoS Biology, 2010
Lantibiotic synthetases are remarkable biocatalysts generating conformationally constrained peptides with a variety of biological activities by repeatedly utilizing two simple posttranslational modification reactions: dehydration of Ser/Thr residues and ...
Yuki Goto, Bo Li, Jan Claesen, Yanxiang Shi, Mervyn J Bibb, Wilfred A van der Donk   +5 more
doaj   +5 more sources

Enantiocomplementary Intramolecular Crossed Aldehyde-Ketone Benzoin Cyclizations Catalyzed by Engineered Benzaldehyde Lyase

Developing unnatural functions and optimizing catalytic properties of enzymes are challenging tasks that require extensive engineering and screening of biocatalysts. In this study, we report the first example of enantiocomplementary intramolecular crossed aldehyde-ketone benzoin cyclizations catalyzed by benzaldehyde lyase.
Ling Yu, Zhijun Song
openaire   +2 more sources

Benzaldehyde Lyase-catalyzed intramolecular benzoin reactions

, 2015
Intramolecular stereoselective carboligations are important reactions in organic synthetic chemistry essential for the access of natural occurring compounds and analogues. Besides the chemical methodologies, a plethora of intramolecular C-C bond forming reactions exists in different metabolic pathways of living organism catalyzed by highly evolved ...
Hernández Sánchez, Karel, Petrillo, Giovanna, Usón, Isabel, Wandtke, Claudia M., Joglar Tamargo, Jesús, Parella, Teodor, Clapés Saborit, Pere, Bujons, Jordi   +7 more
openaire   +2 more sources

The Effect of Chalcone Isomerase Gene Silencing on Pigment Production Pathway in Petunia hybrida with RNAi Technology [PDF]

Majallah-i ̒Ulum-i Bāghbānī, 2023
Introduction  Flower color is one of the most significant characteristics in ornamental plant breeding. New varieties of various plants in relation to their flower color have been obtained by monitoring the expression levels of genes involved or ...
F. Keykha Akhar, A.R. Bagheri, N. Moshtaghi, M. Fakhrfeshani   +3 more
doaj   +1 more source

The genes and enzymes of phosphonate metabolism by bacteria, and their distribution in the marine environment

Frontiers in Microbiology, 2012
Phosphonates are compounds that contain the chemically-stable carbon-phosphorus (C-P) bond. They are widely distributed amongst more primitive life forms including many marine invertebrates and constitute a significant component of the Dissolved Organic
Juan F Villarreal-Chiu, John P. Quinn, John W McGrath   +2 more
doaj   +1 more source

Spatio‐Temporal Processes of Diffusion‐Controlled Communication in Hierarchical Multi‐Compartments

Angewandte Chemie, Volume 137, Issue 26, June 24, 2025.
This study highlights the molecular communication of neighboring biomimetic populations in pH‐responsive hierarchically and non‐covalently organized multi‐compartments (HMC) through the assembly of micro‐ and nanocompartments. HMC unify key roles for cyclic spatio‐temporal diffusion processes and spatio‐temporal enzyme(‐like) reactions.
Xin Qiao, Haixu Chen, Andreas Schurig, Xiaoliang Wang, Yinyong Sun, Matthias Tobler, Susanne Boye, Kathrin Castiglione, Dietmar Appelhans, Xin Huang   +9 more
wiley   +2 more sources

Bioactive polysaccharides and their potential health benefits in reducing the risks of metabolic syndrome: A review

Food Biomacromolecules, EarlyView.
Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo, Evelyne Nkirote Gikundi, Mercy Adhiambo Ndiege, Kevin Omondi Aduol   +3 more
wiley   +1 more source