Results 11 to 20 of about 2,144 (137)

Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I [PDF]

Angewandte Chemie, 2017
AbstractIntramolecular benzoin reactions catalyzed by benzaldehyde lyase from Pseudomonas fluorescens biovar I (BAL) are reported. The structure of the substrates envisaged for this reaction consists of two benzaldehyde derivatives linked by an alkyl chain.
Karel Hernández, Teodor Parella, Giovanna Petrillo, Isabel Usón, Claudia M. Wandtke, Jesús Joglar, Jordi Bujons, Pere Clapés   +7 more
  +7 more sources

Bacterial Conversion of Hydroxylamino Aromatic Compounds by both Lyase and Mutase Enzymes Involves Intramolecular Transfer of Hydroxyl Groups [PDF]

Applied and Environmental Microbiology, 2003
ABSTRACT Hydroxylamino aromatic compounds are converted to either the corresponding aminophenols or protocatechuate during the bacterial degradation of nitroaromatic compounds. The origin of the hydroxyl group of the products could be the substrate itself (intramolecular transfer mechanism) or the solvent water (intermolecular ...
Lloyd J. Nadeau, Zhongqi He, Jim C. Spain   +2 more
openalex   +4 more sources

Enantiocomplementary Intramolecular Crossed Aldehyde-Ketone Benzoin Cyclizations Catalyzed by Engineered Benzaldehyde Lyase [PDF]

Developing unnatural functions and optimizing catalytic properties of enzymes are challenging tasks that require extensive engineering and screening of biocatalysts. In this study, we report the first example of enantiocomplementary intramolecular crossed aldehyde-ketone benzoin cyclizations catalyzed by benzaldehyde lyase.
Ling Yu, Zhijun Song
openalex   +2 more sources

Cupin-Type Dimethylsulfoniopropionate Lyase from Pelagibacter ubique (DddK_Pu) Catalyzes Aza-Michael Addition of Primary and Secondary Amines to Acrylic Acid. [PDF]

Angew Chem Int Ed Engl
A dimethylsulfoniopropionate lyase (DddK) was identified as an efficient aza‐Michaelase for the addition of amines to acrylate. Screening 74 amines with wild‐type DddK and its W26G variant yielded N‐substituted and N,N‐disubstituted β‐amino acids in 30%–93% isolated yield.
Arceri D, Mourelle A, Parella T, Bujons J, Moreno CJ, Clapés P.   +5 more
europepmc   +2 more sources

Bioinformatic characterisation of genes encoding cell wall degrading enzymes in the Phytophthora parasitica genome [PDF]

, 2014
BACKGROUND: A critical aspect of plant infection by the majority of pathogens is penetration of the plant cell wall. This process requires the production and secretion of a broad spectrum of pathogen enzymes that target and degrade the many complex ...
Adrienne R Hardham, Darren P Cullerne, Leila M Blackman   +2 more
core   +2 more sources

Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]

, 1971
Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
core   +1 more source

Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids [PDF]

, 2014
Natural products chemistry has historically been the prime arena for the discovery of new chemical transformations and the fountain of insights into key biological processes.
Boyer N., Boyer N., Coste A., Davis C., Fox E. M., Fukuyama T., Gardiner D. M., Gardiner D. M., Han S., Hauser D., Herscheid J. D. M., Iwasa E., Jiang C.-S., Johnson W. S., Justin Kim, Katagiri K., Kim J., Kim J., Kim J., Kim J., Kirby G. W., Lathrop S. P., Lathrop S. P., Lee S., Miller S. J., Mohammad Movassaghi, Molander G. A., Movassaghi M., Movassaghi M., Movassaghi M., Movassaghi M., Poisel H., Raju R., Robinson R., Sammes P. G., Scharf D. H., Scharf D. H., Scharf D. H., Scharf D. H., Schmidt M. A., Seebach D., Taylor A., Vedejs E., Williams R. M., Woodward R. B.   +44 more
core   +2 more sources

Complexity of the Ruminococcus flavefaciens FD-1 cellulosome reflects an expansion of family-related protein-protein interactions [PDF]

, 2017
This work was supported in part by the European Union, Area NMP.2013.1.1–2: Self-assembly of naturally occurring nanosystems: CellulosomePlus Project number: 604530, and by the EU Seventh Framework Programme (FP7 2007–2013) under the WallTraC project ...
Alves, Victor D, Barak, Yoav, Bayer, Edward A, Borovok, Ilya, Bule, Pedro, Cardoso, Vânia, Dassa, Bareket, Flint, Harry J, Fontes, Carlos M G A, Gilbert, Harry J, Hamberg, Yuval, Israeli-Ruimy, Vered, Jindou, Sadanari, Lamed, Raphael, Moraïs, Sarah, Najmudin, Shabir, Slutzki, Michal, White, Bryan A   +17 more
core   +1 more source

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian, Vasilis Tseliou, Patrick Peters, Tanja Knaus, Francesco G. Mutti   +4 more
wiley   +2 more sources

Enantioselective Intramolecular C-H Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo [PDF]

, 2013
Nitrogen activation: Though P450 enzymes are masters of oxygen activation and insertion into C-H bonds, their ability to use nitrogen for the same purpose has so far not been explored.
Arnold, Frances H., Brown, Tristan R., Coelho, Pedro S., Farwell, Christopher C., Lewis, Jared C., McIntosh, John A., Wang, Z. Jane   +6 more
core   +1 more source