Results 1 to 10 of about 175,835 (341)

Clinical Evaluation over Intranasal Administration of Acepromazine and Diazepam in Pigeons (Columba livia domestica) [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2023
Safe and effective sedation methods are as much momentous for small birds as for other animals not only for surgical procedures but also for safe handling and diagnostic and clinical procedures such as radiography, wound dressing, blood collection, and ...
Nasser Vajdi, Shohreh Alian Samakkhah
doaj   +1 more source

Self-Emulsifying Drug Delivery Systems: An Alternative Approach to Improve Brain Bioavailability of Poorly Water-Soluble Drugs through Intranasal Administration

open access: yesPharmaceutics, 2022
Efforts in discovering new and effective neurotherapeutics are made daily, although most fail to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous solubility, limited permeability through biological membranes ...
Sara Meirinho   +4 more
doaj   +1 more source

Intranasal Vaccination Strategy to Control the COVID-19 Pandemic from a Veterinary Medicine Perspective

open access: yesAnimals, 2021
The world is currently facing an ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease is a highly contagious respiratory disease which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Salleh Annas, Mohd Zamri-Saad
doaj   +1 more source

A Physiologically Based Pharmacokinetic Model for Predicting Diazepam Pharmacokinetics after Intravenous, Oral, Intranasal, and Rectal Applications

open access: yesPharmaceutics, 2021
Diazepam is one of the most prescribed anxiolytic and anticonvulsant that is administered through intravenous (IV), oral, intramuscular, intranasal, and rectal routes.
Sundus Khalid   +9 more
doaj   +1 more source

Intranasal insulin [PDF]

open access: yesJournal of Neuroendocrinology, 2021
Abstract The intranasal (IN) route enables the delivery of insulin to the central nervous system in the relative absence of systemic uptake and related peripheral side effects. Intranasally administered insulin is assumed to travel along olfactory and adjacent pathways and has been shown to rapidly accumulate in cerebrospinal fluid ...
openaire   +3 more sources

Novel Targets and Interventions for Cognitive Complications of Diabetes

open access: yesFrontiers in Physiology, 2022
Diabetes and cognitive dysfunction, ranging from mild cognitive impairment to dementia, often coexist in individuals over 65 years of age. Vascular contributions to cognitive impairment/dementia (VCID) are the second leading cause of dementias under the ...
Victoria Wolf   +5 more
doaj   +1 more source

Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery

open access: yesPharmaceutics, 2023
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles produced from cholesterol and phospholipids. Recently, liposomes have been widely administered intranasally for systemic and brain delivery. From the nasal cavity, liposome-
Van-An Duong   +2 more
doaj   +1 more source

Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs

open access: yesPharmaceutics, 2022
Intranasal administration is a promising route for brain drug delivery. However, it can be difficult to formulate drugs that have low water solubility into high strength intranasal solutions.
Patrícia C. Pires   +3 more
doaj   +1 more source

A comparative study of the effect of intranasal dexamethasone and normal saline on the occurrence of nausea and vomiting after hysterectomy: a clinical trial study [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. Many studies have been performed to prevent nausea and vomiting after surgery with different drugs alone or in combination, but no definite answer has been given yet.
Hamidreza Shetabi   +2 more
doaj   +1 more source

Lipid and Polymeric Nanoparticles: Successful Strategies for Nose-to-Brain Drug Delivery in the Treatment of Depression and Anxiety Disorders

open access: yesPharmaceutics, 2022
Intranasal administration has gained an increasing interest for brain drug delivery since it allows direct transport through neuronal pathways, which can be quite advantageous for central nervous system disorders, such as depression and anxiety ...
Margarida Alberto   +3 more
doaj   +1 more source

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